Results 61 to 70 of about 8,348 (299)

High-resolution mapping of secondary cosmic rays with miniaturised stacked pixel telescope

open access: yesActa Polytechnica
We performed detailed measurements of the secondary cosmic ray field in the lower atmosphere (at 200 m). We use a miniaturised particle telescope consisting of two closely stacked synchronised Timepix3 detectors. Position-, spectral-, and time-sensitive
Carlos Granja   +7 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Silicon detectors for the sLHC [PDF]

open access: yes, 2011
In current particle physics experiments, silicon strip detectors are widely used as part of the inner tracking layers. A foreseeable large-scale application for such detectors consists of the luminosity upgrade of the Large Hadron Collider (LHC), the ...
Tsvetkov, A   +887 more
core   +1 more source

TimeSPOT developments on charged-particle silicon sensors for high intensity 4D-Tracking

open access: yesFrontiers in Sensors
This paper provides a comprehensive overview of recent advances in silicon sensors designed for 4D tracking. These devices are of particular relevance for the next-generation of high intensity collider experiments, where meeting stringent requirements in
A. Lai
doaj   +1 more source

Nuclear Track Detectors. Searches for Exotic Particles [PDF]

open access: yes, 2009
Talk given at "New Trends In High-Energy Physics" (experiment, phenomenology, theory) Yalta, Crimea, Ukraine, September 27-October 4 ...
Giacomelli, G., Togo, V.
openaire   +2 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Particle Detectors: Tracking detectors(1/4) [PDF]

open access: yes, 2016
This lecture course will review the latest advances in high energy physics detector technologies and techniques. The course will feature a lecture each on the main detector types used in the modern particle physics collider experiments, charged particle ...
Bortoletto, Daniela
core  

Jitter Measurements of 1 cm2 LGADs for Space Experiments

open access: yesInstruments
This work explores the possibility of using Low Gain Avalanche Diodes (LGADs) for tracker-based experiments studying Charged Cosmic Rays (CCRs) in space.
Ashish Bisht   +7 more
doaj   +1 more source

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