Results 211 to 220 of about 4,659,820 (378)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

The individuation of mathematical objects. [PDF]

Synthese
Assadian B, Fraser R.
europepmc   +1 more source

Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tail. [PDF]

, 1990
Mark A. Williams, Minoru Fukuda
openalex   +1 more source

Platelets get particular

Blood, 2022
Lubica Rauova, Douglas B. Cines
openaire   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Unending dialectical politics of identity in Ethiopia. [PDF]

F1000Res
Assefa T.
europepmc   +1 more source

Ethical Relativism and Circumstances of Social and Cultural Contingencies on Informed Consent in the Conduct of Research: Clinical Trials in Nigeria. [PDF]

Asian Bioeth Rev, 2023
Aluko-Arowolo S, Lawal SA, Adedeji IA, Nwaobilor S.   +3 more
europepmc   +1 more source

A liderança em Instituições Particulares de Solidariedade Social : uma análise de géneros

, 2016
Serralha, Joana Martins
openalex   +1 more source

Design of a photo-written cavity neodymium doped fibre laser, tunable around a particular absorption molecular line

, 1994
G. Martinelli, M. Douay, P. Bernage, P. Niay, Jean‐Francois Henninot, P. Carette, J.F. Bayon   +6 more
openalex   +2 more sources