Results 111 to 120 of about 2,334,761 (307)

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li   +21 more
wiley   +1 more source

Electrochemical Characteristics of Particulate Matter

open access: yes
The current work is dedicated to electrochemical impedance spectra analysis of the fine and coarse airborne particulate matter sampled on the glass fibre filters in Riga city air.
Baitimirova, Margarita   +3 more
core  

Particulate matter and heart disease

open access: yes, 2004
Particulate matter and heart ...
Anna Peeters (13058832)
core  

(Table 4) Fluxes of 234Th and suspended particulate matter in sediment traps from the Kara Sea

open access: yes, 1995
(Table 4) Fluxes of 234Th and suspended particulate matter in sediment traps from the Kara ...
Vladimir P Shevchenko (6885425)   +5 more
core   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

open access: yesAdvanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong   +17 more
wiley   +1 more source

Hydrogen peroxide serves as pivotal fountainhead for aerosol aqueous sulfate formation from a global perspective

open access: yesNature Communications
Traditional atmospheric chemistry posits that sulfur dioxide (SO2) can be oxidized to sulfate (SO4 2–) through aqueous-phase reactions in clouds and gas-phase oxidation.
Jie Gao   +8 more
doaj   +1 more source

Composition and age of suspended particulate and dissolved organic matter in the Lena River and Central Siberian Rivers, 2002-2014

open access: yes
This data set consists of isotopic and molecular information obtained from samples of particulate and dissolved organic matter collected throughout the ice-free season in the Lena River Delta, supplemented with samples from Central Siberian Rivers ...
Mollenhauer, Gesine
core   +1 more source

(Table 1) Group composition of carbohydrates from surface particulate matter of the Northwest Pacific

open access: yes, 1973
(Table 1) Group composition of carbohydrates from surface particulate matter of the Northwest ...
Vladlen E Artem'ev (7945994)   +1 more
core   +1 more source

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu   +10 more
wiley   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

open access: yesAdvanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu   +10 more
wiley   +1 more source

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