Results 51 to 60 of about 176,534 (249)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Through the Lens of Time: The Partition in Krishna Sobti’s Autobiography, "From Gujrat, Pakistan, to Gujrat, India"

open access: yesCracow Indological Studies, 2018
Through the Lens of Time: The Partition in Krishna Sobti’s Autobiography, "From Gujrat, Pakistan, to Gujrat, India" In her latest book, Gujrāt Pakistān se Gujrāt Hindustān tak (2017), Krishna Sobti (b.
Maria Skakuj-Puri
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

PARTIȚIA INDIEI. PROVOCĂRI ÎN DOMENIUL SECURITĂȚII NAȚIONALE ÎN INDIA INDEPENDENTĂ [PDF]

open access: yesIntelligence și Cultura de Securitate, 2022
The aim of this research is to approach, from an historic perspective, the events that occurred in 1947 on the current territory of India and Pakistan. The 20th century marks a new start for India, following two events that determined the fate of the ...
Alexandra-Iulia NUC
doaj  

Partition Expanders

open access: yesTheory of Computing Systems, 2016
We introduce a new concept, which we call partition expanders. The basic idea is to study quantitative properties of graphs in a slightly different way than it is in the standard definition of expanders. While in the definition of expanders it is required that the number of edges between any pair of sufficiently large sets is close to the expected ...
Gavinsky, Dmitry, Pudlák, Pavel
openaire   +6 more sources

POWER PARTITIONS AND SEMI--FIBONACCI PARTITIONS

open access: yesBulletin of the Australian Mathematical Society, 2020
Andrews [‘Binary and semi-Fibonacci partitions’, J. Ramanujan Soc. Math. Math. Sci.7(1) (2019), 1–6] recently proved a new identity between the cardinalities of the set of semi-Fibonacci partitions and the set of partitions into powers of 2 with all parts appearing an odd number of times.
ABDULAZIZ M. ALANAZI   +2 more
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Alienação e separação: elementos para discussão de um caso clínico Alienación y separación: elementos para discusión de un caso clínico Alienation and partition: elements for discussion of a clinical case

open access: yesPsicologia em Estudo, 2011
Este artigo discute a causação do sujeito a partir dos conceitos de “alienação” e “separação” na perspectiva lacaniana, valendo-se da análise de um caso clínico da literatura psicanalítica recente.
Maria Angélica Mello Pisetta   +1 more
doaj   +1 more source

Probabilistic Partitive Partitioning (PPP)

open access: yes, 2020
Clustering is a NP-hard problem. Thus, no optimal algorithm exists, heuristics are applied to cluster the data. Heuristics can be very resource-intensive, if not applied properly. For substantially large data sets computational efficiencies can be achieved by reducing the input space if a minimal loss of information can be achieved.
openaire   +2 more sources

Hypergraph Partitioning [PDF]

open access: yes, 2011
Hypergraphs are generalization of graphs where each edge (hyperedge) can connect more than two vertices. In simple terms, the hypergraph partitioning problem can be defined as the task of dividing the vertices of hypergraph into two or more roughly equal sized parts such that a cost function on the hyperedges connecting vertices in different parts is ...
Quincey Koziol   +13 more
openaire   +3 more sources

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