Results 211 to 220 of about 72,047 (264)

Electrochemical Determination of Partition Coefficients of Drugs

Journal of Pharmaceutical Sciences, 1992
An electrochemical method for the determination of partition coefficients of drugs that can exist as ions in aqueous solutions is presented. The method involves cyclic voltammetry at the polarizable interface between two immiscible electrolyte solutions.
K, Kontturi, L, Murtomäki
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Liquid/Air Partition Coefficients of the Trimethylbenzenes

Toxicology and Industrial Health, 1995
Liquidlair partition coefficients (λ) of the three isomers of trimethylbenzene (1,2,3-, 1,2,4-, and 1,3,5-TMB) were determined in vitro using automated head space gas chromatography. The liquids used were water (physiological saline), fresh human blood, and olive oil.
J, Järnberg, G, Johanson
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Partition Coefficients for Benzene in Human Skin

AIHAJ, 2002
The contribution of benzene to body burden after skin absorption compared with that due to inhalation absorption is of potential interest in the setting and interpretation of benzene (inhalation) exposure standards. However, an understanding of the quantitative relationship between skin and inhalation absorption, under different exposure conditions, is
Georgia C, Sinclair, Ronald C, Wester, Howard I, Maibach   +2 more
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Partition coefficients of acyclic graphs

1995
We develop the concept of a “closure space”; which appears with different names in many aspects of graph theory. We show that acyclic graphs can be almost characterized by the partition coefficients of their associated closure spaces. The resulting nearly total ordering of all acyclic graphs (or partial orders) provides an effective isomorphism filter ...
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Variation of Partition Coefficient

Nature, 1965
MATSUI and I have estimated partition coefficients for some elements1–4 and discussed the significance5,6 of estimating them. More recently7, I have estimated partition coefficients for rubidium and strontium. However, we have little knowledge about what conditions affect partition coefficients and to what extent they can be influenced. For example, it
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Partition Coefficients of Three New Anticonvulsants

Journal of Pharmaceutical Sciences, 1990
The partition coefficients of three homologous anticonvulsant phenylalkylamides [racemic alpha-hydroxy-alpha-ethyl-alpha-phenylacetamide (HEPA); beta-hydroxy-beta-ethyl-beta-phenylpropionamide (HEPP); and gamma-hydroxy-gamma-ethyl-gamma-phenylbutyramide (HEPB)] were determined by reversed-phase high-performance liquid chromatography (RP-HPLC).
Z, Hernandez-Gallegos, P A, Lehmann
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Partition Coefficients of Organic Contaminants with Carbohydrates

Environmental Science & Technology, 2010
In view of the current lack of reliable partition coefficients for organic compounds with carbohydrates (K(ch)), carefully measured values with cellulose and starch, the two major forms of carbohydrates, are provided for a wide range of compounds: short-chain chlorinated hydrocarbons, halogenated benzenes, alkyl benzenes, polycyclic aromatic ...
Hsu-Wen, Hung, Tsair-Fuh, Lin, Cary T, Chiou   +2 more
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The influence of hydrogen bonding on partition coefficients

Journal of Computer-Aided Molecular Design, 2017
This Perspective explores how consideration of hydrogen bonding can be used to both predict and better understand partition coefficients. It is shown how polarity of both compounds and substructures can be estimated from measured alkane/water partition coefficients.
Nádia Melo Borges, Peter W. Kenny, Carlos Alberto Montanari, Igor M. Prokopczyk, Jean F. R. Ribeiro, Josmar R. Rocha, Geraldo Rodrigues Sartori   +6 more
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Selected noble-gas partition coefficients

Physics in Medicine and Biology, 1985
The Ostwald solubility of 41Ar, 127,133Xe, N13N and CH3 18F in water, saline, blood, plasma, lipids, benzene and bone were measured in vitro. In addition the bone-blood partition coefficients for these gases were determined. For 41Ar, the bone-blood partition function is found to be 1.1 +/- 0.3, whereas for xenon the bone-blood partition coefficient is
M S, Rosenthal, R J, Nickles
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MembraneiBuffer Partition Coefficient for Ethanol in Dimyristoylphosphatidylcholine

Alcoholism: Clinical and Experimental Research, 1981
Phase transitions of dimyristoylphosphatidylcholine (DMPC) are followed using optical density measurements, as a function of aqueous ethanol concentration. The shift of the phase transition to lower temperatures is interpreted in terms of the thermodynamics of freezing point depressions.
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