Results 41 to 50 of about 71,535 (264)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Prediction of Partition Coefficients of Organic Compounds for SPME/PDMS
MATEC Web of Conferences, 2016 The partition coefficients of 51 organic compounds between SPME/PDMS and gas were compiled from the literature sources in this study. The effect of physicochemical properties and descriptors on the partitioning process of partition coefficients was ...
Liao Hsuan-Yu +3 more
doaj +1 more source
The Effect of Ring Size on the Biological Activity of Nitrogen Containing Compounds
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2012 The biological activity of N-containing ring compounds was studied as a function of the distribution coefficient of these compounds in 1-octanol/water system.
Sowdani K.M.
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
EXPERIMENTALl ANALYSIS OF PARTITION COEFFICIENT IN Al-Mg ALLOYS
Iranian Journal of Materials Science and Engineering, 2016 Because the partition coefficient is one of the most important parameters affecting microsegregation, the aim of this research is to experimentally analyse the partition coefficient in Al-Mg alloys.
M.H. Avazkonandeh-Gharavo +2 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Effect of formulation factors on in vitro transcorneal permeation of voriconazole from aqueous drops
Journal of Advanced Pharmaceutical Technology & Research, 2013 The purpose of this research was to evaluate the effect the formulation factors on in vitro permeation of voriconazole through freshly isolated goat and sheep corneas.
Biswaranjan Mohanty +2 more
doaj +1 more source
Sylow Branching Coefficients and Hook Partitions
Vietnam Journal of Mathematics, 2023 AbstractWe give a description of the irreducible constituents of the restriction to Sylow 2-subgroups of irreducible characters of symmetric groups labelled by hook partitions.
Giannelli E., Volpato G.
openaire +2 more sources
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source