Results 71 to 80 of about 75,572 (265)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

One-Dimensional Vertex Models Associated with a Class of Yangian Invariant Haldane-Shastry Like Spin Chains

Symmetry, Integrability and Geometry: Methods and Applications, 2010
We define a class of Y(sl_{(m|n)}) Yangian invariant Haldane-Shastry (HS) like spin chains, by assuming that their partition functions can be written in a particular form in terms of the super Schur polynomials.
Kazuhiro Hikami, Nilanjan Bondyopadhaya, Bireswar Basu-Mallick   +2 more
doaj   +1 more source

Trinion conformal blocks from topological strings

Journal of High Energy Physics, 2020
In this paper we investigate the relation between conformal blocks of Liouville CFT and the topological string partition functions of the rank one trinion theory T 2.
Ioana Coman, Elli Pomoni, Joerg Teschner
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

5d/6d DE instantons from trivalent gluing of web diagrams

Journal of High Energy Physics, 2017
We propose a new prescription for computing the Nekrasov partition functions of five-dimensional theories with eight supercharges realized by gauging non-perturbative flavor symmetries of three five-dimensional superconformal field theories.
Hirotaka Hayashi, Kantaro Ohmori
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Supersymmetric analogue of BCN type rational integrable models with polarized spin reversal operators

Nuclear Physics B, 2016
We derive the exact spectra as well as partition functions for a class of BCN type of spin Calogero models, whose Hamiltonians are constructed by using supersymmetric analogues of polarized spin reversal operators (SAPSRO).
P. Banerjee, B. Basu-Mallick, N. Bondyopadhaya, C. Datta   +3 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

2D CFT partition functions at late times

Journal of High Energy Physics, 2017
We consider the late time behavior of the analytically continued partition function Z(β + it)Z(β − it) in holographic 2d CFTs. This is a probe of information loss in such theories and in their holographic duals.
Ethan Dyer, Guy Gur-Ari
doaj   +1 more source