Results 111 to 120 of about 2,156 (246)
La Revue explore de nouveaux domaines. [PDF]
Can J Sci Math and Technol Educ, 2021 McDougall D.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Considerations on the programmed functional life (one generation) of a green artificial reef in terms of the sustainability of the modified ecosystem. [PDF]
Heliyon, 2023 Carral L +5 more
europepmc +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Vene ja eesti üliõpilaste valikud täis- ja osasihitise kasutamisel
Lähivõrdlusi, 2010 The article compares the use of total and partial objects by L2 and L1 speakers of Estonian. For the purposes of the article, L2 speakers of Estonian are native speakers of Russian who are pursuing a programme of studies in Estonian as a foreign language
Raili Pool
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Genesis of the Genitive of Negation in Balto-Slavic and Its Evidence in Contemporary Slovenian
Slovenski Jezik - Slovene Linguistic Studies, 2019 Genitive of negation is a Balto-Slavic syntactic rule that governs the transformation of accusative complements of transitive verbs or subjects of existential constructions in positive sentences to genitive complements in negative sentences.
Žiga Pirnat
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Language and the Moving Body: Directive Actions With the Finnish kato "look" in Nature-Related Activities. [PDF]
Front Psychol, 2021 Siitonen P, Rauniomaa M, Keisanen T.
europepmc +1 more source