Qualities, objects, sorts, and other treasures : gold digging in English and Arabic [PDF]
In the present monograph, we will deal with questions of lexical typology in the nominal domain. By the term "lexical typology in the nominal domain", we refer to crosslinguistic regularities in the interaction between (a) those areas of the lexicon ...
Behrens, Leila, Sasse, Hans-Jürgen
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Cross-Linguistic Trade-Offs and Causal Relationships Between Cues to Grammatical Subject and Object, and the Problem of Efficiency-Related Explanations. [PDF]
Levshina N.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
English Adjectives and Estonian Nouns: Looking for Agreement? [PDF]
Bahtina D, Kask H, Verschik A.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Combining statistical and semantic approaches to the translation of ontologies and taxonomies [PDF]
Ontologies and taxonomies are widely used to organize concepts providing the basis for activities such as indexing, and as background knowledge for NLP tasks.
Aguado de Cea, G. +4 more
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Why “Partitive Articles” Do Not Exist in (Old) Spanish [PDF]
Gerards, David, Stark, Elisabeth
openaire +2 more sources

