Results 41 to 50 of about 1,543,646 (293)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Developing a collaborative research partnership [PDF]

Nursing Standard, 2015
This article details a collaborative research project undertaken in an acute NHS foundation trust, in partnership with a local higher education institution (HEI). The article identifies enablers and challenges to working in this type of collaboration and discusses the implications for the development of similar projects.
Beddingham, Elaine, Whitehead, Bill
openaire   +3 more sources

Partnership research with older people: moving towards making the rhetoric a reality [PDF]

, 2004
As nursing develops closer partnerships with older people in delivering care, it also needs to develop partnerships in order to create the knowledge base for practice in a way that challenges professional hegemony and empowers older people.
Barnes M., Carter T., Cooperrider D.L., Goodacre H., Reed J., Reed J., Reed J., Rolfe G., Rolfe G., Tetley J.   +9 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Setting strategy for system change: using concept mapping to prioritise national action for chronic disease prevention

Health Research Policy and Systems, 2017
Background Chronic diseases are a serious and urgent problem, requiring at-scale, multi-component, multi-stakeholder action and cooperation. Despite numerous national frameworks and agenda-setting documents to coordinate prevention efforts, Australia ...
Sonia Wutzke, Nick Roberts, Cameron Willis, Allan Best, Andrew Wilson, William Trochim   +5 more
doaj   +1 more source

Mild reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant: First case report from Indonesia

Frontiers in Medicine, 2022
BackgroundReinfection with SARS-CoV-2 has been well documented, yet little is known about the degree of protection a previous infection provides against reinfection, especially against Variants of Concern (VOC).Case presentationHere we describe a case of
Naniek Isnaini, Yan Mardian, Dewi Lokida, Dewi Lokida, Fajar Budiono, Deni P. Butar-butar, Dona Arlinda, Dona Arlinda, Gustiani Salim, Herman Kosasih, Wahyu Nawang Wulan, Jacqueline Perodin, Aaron Neal, H. Clifford Lane, Muhammad Karyana, Muhammad Karyana   +15 more
doaj   +1 more source

Librarian readiness for research partnerships [PDF]

Journal of the Medical Library Association : JMLA, 2015
This study investigated health sciences librarians' knowledge and skill-based readiness to partner on sponsored research involving human participants. The authors developed and deployed, at two time points, a web-based survey on nine indicators of research activities with response choices reflecting the transtheoretical model of stages of behavior ...
Emily S, Mazure, Kristine M, Alpi
openaire   +2 more sources