Results 81 to 90 of about 392,884 (306)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Open Space – a collaborative process for facilitating Tourism IT partnerships [PDF]
, 2008 The success of IT projects depends on the success of the partnerships on which they are based. However past research by the author has identified a significant rate of failure in these partnerships, predominantly due to an overly technical mindset ...
Philip Alford, Alford, Philip
core +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
State of Ohio Fiscal Year ... consolidated plan annual performance report
, 2001 Electronic coverage as of Oct. 15, 2005: 2000-; Description based on: 2000; title from PDF cover (viewed on Oct. 15, 2007).; Latest issue consulted: 2005.; Report year runs July 1st to June 30th.; Harvested from the web on 10/15 ...
Ohio. Office of Housing and Community Partnerships.
core
Natural language processing to identify lupus nephritis phenotype in electronic health records
BMC Medical Informatics and Decision MakingBackground Systemic lupus erythematosus (SLE) is a rare autoimmune disorder characterized by an unpredictable course of flares and remission with diverse manifestations. Lupus nephritis, one of the major disease manifestations of SLE for organ damage and
Yu Deng +18 more
doaj +1 more source
Foods, 2019 Studying consumers’ implicit emotions has been always described as a difficult and a complicated mission due to the emotions being of a non-cognitive nature.
Diana Ismael, Angelika Ploeger
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
An Exploration of Hmong Women's Perspectives on Cancer
Asian Nursing Research, 2008 The purpose of this study was to explore the perspectives of Hmong women on cancer, using focus groups as the research method. Methods: Two focus group interviews were conducted and the narrative data were analyzed using thematic content analysis ...
Mary Jo Baisch, PhD, RN +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source