Results 201 to 210 of about 1,657,465 (298)

How do mass shootings shape the social media discourse on guns in the US Congress? Causal discovery and topic modeling. [PDF]

PLOS Glob Public Health
Bukhanevych D, Succar R, Porfiri M.
europepmc   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Research on the double-edged effect of intelligent algorithm recommendation on shaping college students' values and the path of collaborative governance. [PDF]

PLoS One
Geng Y, Li Z.
europepmc   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Game theoretic modeling and optimization of competition and collaboration in dual channel electronic waste supply chains. [PDF]

Sci Rep
Wang C, Shi J, Wang K.
europepmc   +1 more source

Low‐intervention clinical trials in Spain: Do they progress?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Low‐Intervention Clinical Trials (LICTs) are generally pragmatic trials that investigate medicinal products already authorized for use. In 2014, simplified regulatory frameworks were introduced for LICTs with the aim of reducing regulatory burden and operational complexity, to foster non‐commercial clinical trials (NCCTs); the mandatory ...
Claudia Erika Delgado‐Espinoza, Mayro J. Cortés Pestana, Kristopher Amaro, Rosa M. Antonijoan, Caridad Pontes   +4 more
wiley   +1 more source

THE ТYPOLOGICAL SPECIFICITIES OF PARTY SYSTEMS

Вісник Харківського національного університету імені В. Н. Каразіна: Серія "Питання політології", 2018
Sutula O.
doaj  

Distributed storage database system for motion data based on blockchain technology. [PDF]

Sci Rep
Wang P, Zhao Z.
europepmc   +1 more source

Verticox+: vertically distributed Cox proportional hazards model with improved privacy guarantees. [PDF]

Complex Intell Systems
van Daalen F, Smits D, Ippel L, Dekker A, Bermejo I.   +4 more
europepmc   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source