Structural studies of Parvoviridae capsid assembly and evolution: implications for novel AAV vector design [PDF]
Adeno-associated virus (AAV) vectors have emerged as powerful tools in gene therapy, potentially treating various genetic disorders. Engineering the AAV capsids through computational methods enables the customization of these vectors to enhance their ...
Heather A. Noriega +3 more
doaj +5 more sources
ICTV Virus Taxonomy Profile: Parvoviridae [PDF]
Members of the family Parvoviridae are small, resilient, non-enveloped viruses with linear, single-stranded DNA genomes of 4–6 kb. Viruses in two subfamilies, the Parvovirinae and Densovirinae, are distinguished primarily by their respective ability to infect vertebrates (including humans) versus invertebrates.
Cotmore, Susan F. +15 more
core +9 more sources
A set of proposals to rationalize and extend the taxonomy of the family Parvoviridae is currently under review by the International Committee on Taxonomy of Viruses (ICTV). Viruses in this family infect a wide range of hosts, as reflected by the longstanding division into two subfamilies: the Parvovirinae, which contains viruses that infect vertebrate ...
Cotmore, Susan F. +10 more
openaire +5 more sources
Maternal health status is associated with paired maternal and cord blood virome and mother-to-infant transmission [PDF]
The viromes of maternal peripheral blood (MPB) and umbilical cord blood (UCB) provide crucial insights into mother-to-infant transmission and the associations of maternal health with early-life viral colonization.
Xiaofei Song +20 more
doaj +2 more sources
A Novel Parvovirus Associated with the Whitefly Bemisia tabaci [PDF]
The whitefly Bemisia tabaci (Hemiptera: Aleyrodoidea) causes direct feeding damage to crop plants and transmits pathogenic plant viruses, thereby threatening global food security.
Fani Gousi +4 more
doaj +2 more sources
Geographic and Molecular Insights Into Bat Diversity and Virus Distribution in China: Implications for Public Health [PDF]
ABSTRACT Bats are key reservoirs of zoonotic viruses, yet comprehensive data on their diversity and viral carriage across China remain limited. This study compiled national‐level data on bat taxonomy, distribution, and associated viruses by integrating information from peer‐reviewed publications (PubMed), the ZOVER database, and cytochrome oxidase I ...
Yameng Xu +16 more
wiley +2 more sources
Comparative analysis of fecal DNA viromes in Large-billed crows and Northern ravens reveals diverse viral profiles [PDF]
As facultative scavenger birds, crows carry various parasites, viruses, and bacteria, making them significant infection hosts and transmission vectors.
Yonggang Dong +7 more
doaj +3 more sources
Molecular characterization of the newly identified human parvovirus 4 in the family Parvoviridae
Human parvovirus 4 (PARV4) is an emerging human virus, and little is known about the molecular aspects of PARV4 apart from its incomplete genome sequence, which lacks information of the termini. We analyzed the gene expression profile of PARV4 using a nearly full-length HPV4 genome in a replication competent system in 293 cells.
Lou, Sai +9 more
openaire +3 more sources
Capsid Structure of the Fish Pathogen Syngnathus Scovelli Chapparvovirus Offers a New Perspective on Parvovirus Structural Biology [PDF]
Chapparvoviruses (ChPVs) comprise a divergent lineage of the Parvoviridae ssDNA virus family and evolved to infect vertebrate animals independently from the Parvovirinae subfamily.
Judit J. Penzes, Jason T. Kaelber
doaj +2 more sources
Parvoviruses of Invertebrates (Parvoviridae)
A wide spectrum of invertebrates is susceptible to various linear single-stranded DNA viruses. Their complexity of replication results in a strong dependence on actively dividing cells. They are usually highly pathogenic for invertebrates (Hexapoda, Decapoda, Echinodermata, etc.).
Pénzes, Judit J +4 more
openaire +3 more sources

