Results 51 to 60 of about 9,053 (218)

The role of nuclear localization signal in parvovirus life cycle

open access: yesVirology Journal, 2017
Parvoviruses are small, non-enveloped viruses with an approximately 5.0 kb, single-stranded DNA genome. Usually, the parvovirus capsid gene contains one or more nuclear localization signals (NLSs), which are required for guiding the virus particle into ...
Peng Liu   +3 more
doaj   +1 more source

Phylogeny and evolution of porcine parvovirus

open access: yesVirus Research, 2013
Porcine parvovirus (PPV), a member of the genus Parvovirus, family Parvoviridae, is a significant causative agent in porcine reproductive failure, causing serious economic losses in the swine industry. Previous phylogenetic studies based on the NS1 or VP2 genes indicated that current PPV strains diverged 30 years ago and that VP2 was under neutral or ...
Ren, Xiaofeng   +5 more
openaire   +3 more sources

ACTUAL INFECTIOUS DISEASES IN BULGARIAN PIG INDUSTRY

open access: yesArchives of Veterinary Medicine, 2009
At the moment the most important diseases for Bulgarian pig industry are classical swine fever and Aujeszky’s disease in respect of which we are obliged to meet the require ments of the European Union (EU) as well as Porcine reproductive and respiratory ...
Angel Mortrovski   +2 more
doaj   +1 more source

Cellular adaptive immune response against porcine circovirus type 2 in subclinically infected pigs [PDF]

open access: yes, 2009
Background Porcine circovirus type 2 (PCV2) is a dominant causative agent of postweaning multisystemic wasting syndrome (PMWS), a multifactorial disease complex with putative immunosuppressive characteristics. Little is known about adaptive PCV2-specific
Gerber Heidi   +4 more
core   +1 more source

Current Status of Kidney Xenotransplantation in Basic Research

open access: yesOrgan Medicine, EarlyView.
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley   +1 more source

Novel parvoviruses in reptiles and genome sequence of a lizard parvovirus shed light on Dependoparvovirus genus evolution. [PDF]

open access: yes, 2015
Here, we report the detection and partial genome characterization of two novel reptilian parvoviruses derived from a short-tailed pygmy chameleon (Rampholeon brevicaudatus) and a corn snake (Pantherophis guttatus) along with the complete genome analysis ...
Benkő, Mária   +3 more
core   +3 more sources

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

open access: yesBritish Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu   +6 more
wiley   +1 more source

Determination of optimum nanofiltration conditions for the manufacturing process of human normal immunoglobulin G for intravenous administration

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. Medicinal products based on immunoglobulin class G (IgG) from human plasma are widely used in clinical practice to treat bacterial and viral infections, primary and secondary immunodeficiencies, and autoimmune diseases ...
N. V. Zubkova   +8 more
doaj   +1 more source

Differential expression of microRNAs in porcine parvovirus infected porcine cell line [PDF]

open access: yesVirology Journal, 2015
Porcine parvovirus (PPV), a member of the Parvoviridae family, causes great economic loss in the swine industry worldwide. MicroRNAs (miRNAs) are a class of non-protein-coding genes that play many diverse and complex roles in viral infections.Aiming to determine the impact of PPV infections on the cellular miRNAome, we used high-throughput sequencing ...
Li, Xinqiong   +9 more
openaire   +2 more sources

Co-Infection of Swine with Porcine Circovirus Type 2 and Other Swine Viruses

open access: yesViruses, 2019
Porcine circovirus 2 (PCV2) is the etiological agent that causes porcine circovirus diseases and porcine circovirus-associated diseases (PCVD/PCVAD), which are present in every major swine-producing country in the world.
Ting Ouyang   +3 more
doaj   +1 more source

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