Results 81 to 90 of about 96,485 (242)

Sex‐Specific Associations of Inflammatory Biomarkers With All‐Cause and Cardiovascular Mortality Across Glycaemic Status: A Prospective UK Biobank Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang   +5 more
wiley   +1 more source

BioRePortAP, an electronic clinical record coupled with a database : an example of its use in a single [PDF]

open access: yes, 2010
Aims: To evaluate the efficacy and safety of the treatment of psoriatic arthritis (PsA) patients with tumor necrosis factor (TNF) antagonists in the Rheumatology Department of Hospital de Santa Maria using the BioRePortAP.
Campanilho-Marques, R.   +9 more
core  

Super‐Response to Guselkumab Treatment in Patients With Moderate‐to‐Severe Psoriasis: Real‐World Data With Up to Five Years of Follow‐Up in The Czech Republic

open access: yesInternational Journal of Dermatology, EarlyView.
Super‐response to Guselkumab. ABSTRACT Background Guselkumab, a selective interleukin (IL)‐23 inhibitor, is approved for the treatment of moderate‐to‐severe plaque psoriasis. While randomized clinical trials have introduced the concept of “super‐responders” (SRe)—patients achieving complete skin clearance (Psoriasis Area and Severity Index [PASI] 100 ...
Martina Kojanova   +76 more
wiley   +1 more source

Dynamical interplay between awareness and epidemic spreading in multiplex networks

open access: yes, 2013
We present the analysis of the interrelation between two processes accounting for the spreading of an epidemics, and the information awareness to prevent its infection, on top of multiplex networks.
Arenas, Alex   +2 more
core   +2 more sources

T-cell modulation for the treatment of chronic plaque psoriasis with efalizumab (Raptiva (TM)): Mechanisms of action [PDF]

open access: yes, 2004
Psoriasis is a chronic, incurable, auto-immune disorder with cutaneous manifestations. New evidence on the central role of the immune system in the pathogenesis of psoriasis increasingly provides insight into pathogenic steps that can be modulated to ...
Caro, I.   +7 more
core   +1 more source

Reduced Gr\"obner Bases of Certain Toric Varieties; A New Short Proof [PDF]

open access: yes, 2010
Let K be a field and let m_0,...,m_{n} be an almost arithmetic sequence of positive integers. Let C be a toric variety in the affine (n+1)-space, defined parametrically by x_0=t^{m_0},...,x_{n}=t^{m_{n}}.
Al-Ayyoub, Ibrahim
core  

Chemical freeze-out temperature in hydrodynamical description of Au+Au collisions at sqrt(s_NN) = 200 GeV

open access: yes, 2008
We study the effect of separate chemical and kinetic freeze-outs to the ideal hydrodynamical flow in Au+Au collisions at RHIC (sqrt(s_NN) = 200 GeV energy).
A. Andronic   +41 more
core   +1 more source

Superior Clinical and Economic Value of IL‐23 Inhibitors Versus Adalimumab Biosimilars in Plaque Psoriasis

open access: yesInternational Journal of Dermatology, EarlyView.
A bicentric retrospective real‐world study (N = 616) comparing IL‐23 inhibitors (guselkumab, risankizumab, tildrakizumab) with adalimumab biosimilars in moderate‐to‐severe plaque psoriasis. It presents PASI90 response at Weeks 16 and 52, NNT, and cost‐effectiveness (incremental cost per responder, CE plane, CEAC/CEAF).
Gennaro Marco Falco   +13 more
wiley   +1 more source

Clinical and economic analysis of biologic drugs in treatment of psoriasis

open access: yesКачественная клиническая практика, 2018
Purpose. To evaluate the cost effectiveness of use of ustekinumab (Stelara®), infliximab (Remicade®) and adalimumab (Humira®) for treatment of moderate and severe psoriasis. Methods.
A. A. Kubanov   +2 more
doaj  

The role of kynurenine and kynurenine metabolites in psoriasis

open access: yesTürk Biyokimya Dergisi
Psoriasis is a widespread immunological disease characterised by inflammation and primarily associated with skin and joint symptoms. The kynurenine pathway significantly influences inflammation and immune system activity.
Akyurek Fikret   +2 more
doaj   +1 more source

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