Results 111 to 120 of about 287,667 (257)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Deconstructing the mixed-race experience of passing

, 2013
Committee Members: Susie Lan Cassel (Chair), Dawn M Formo, Salah MoukhlisIn "Beauty and the Beast: On Racial Ambiguity" Carla Bradshaw\ud describes passing as an attempt to achieve acceptability by claiming\ud membership in some desired group while ...
Segall, Victoria Baldo
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Overview : passing off

, 2013
The tort of passing off is concerned with the misappropriation by deception of a trader’s reputation or goodwill. Original, the action was confined to fraudulent attempts by trades to pass off their goods as those of another.
Ireland, Jennifer L. (R17644)
core  

An auditory dataset of passing vehicles recorded with a smartphone

, 2018
.mp4 files and .wav files corresponding to the paper 'An auditory dataset of passing vehicles recorded with a smartphone' Also included is a MATLAB m-file that produces the figures in the ...
Schoustra, M. (Michael), de Winter, J.C.F. (Joost), van der Aa, A. (Arne), Bazilinskyy, P. (Pavlo), van der Vlist, K.J. (Klaas Jan), Spruit, J. (John), Staats, L. (Laurens)   +6 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

SOME OF THE ATHLETIC MOVEMENTS AS THE BASE FOR THE MOTORIC ABILITY OF THE TOP-CLASS FOOTBALLERS [PDF]

Sport Mont, 2007
It is generally known that a footballer must have a certain developmental level of the physical abilities so he could more easily move in the fi eld. During a game, footballers actively possess the ball for about 60-65 minutes, and at the average they ...
Rade Stefanović, Vesko Milenković
doaj