Results 121 to 130 of about 664,076 (315)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

"Passing and the fluidity of race. An analysis of Nella Larsen's narrative."

open access: yes
reservedL'argomento centrale della tesi sarà il passing, un fenomeno storico, sociale e culturale che ha caratterizzato alcuni membri della comunità afro-americana degli anni '20 e '30 del Novecento.
ZAMPIERI, ILARIA
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

SOME OF THE ATHLETIC MOVEMENTS AS THE BASE FOR THE MOTORIC ABILITY OF THE TOP-CLASS FOOTBALLERS [PDF]

open access: yesSport Mont, 2007
It is generally known that a footballer must have a certain developmental level of the physical abilities so he could more easily move in the fi eld. During a game, footballers actively possess the ball for about 60-65 minutes, and at the average they ...
Rade Stefanović, Vesko Milenković
doaj  

The effects of fatigue on soccer skills performed during a soccer match simulation [PDF]

open access: yes, 2011
Purpose: This study examined the effects of exercise-induced fatigue on soccer skills performed throughout simulated match play. Methods: Fifteen academy soccer players completed a soccer match simulation (SMS) including passing, dribbling, and shooting ...
Benton, David   +8 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Analysis of basic soccer techniques for Junior High School extracurricular players

open access: yesSriwijaya Journal of Sport
Basic technical ability is an important element for soccer players. However, analysis of these skills for beginners are very rarely done. Even though with the analysis, the coach can help to optimize the game of the novice team. The research conducted is
Riko Riko   +2 more
doaj   +1 more source

The Passing of Postmodernism A Spectroanalysis of the Contemporary

open access: yes
Examines the increasingly prevalent assumption that postmodernism is over and that literature and film are once again engaging sincerely with issues of ethics and politics.The Passing of Postmodernism: A Spectroanalysis of the Contemporary -- The Passing
Toth, Josh.
core  

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