Results 31 to 40 of about 38,832 (252)

Analysis of Passive Shielding Performance Stability in Hybrid Magnetic Shielding Devices

open access: yesApplied Sciences
In hybrid active–passive magnetic shielding systems, active compensation coils are used to suppress residual magnetic fields inside the shield. However, due to the intrinsic hysteresis of high-permeability materials, the compensation fields inevitably ...
Shicheng Yu   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Angular acceleration compensation guidance law for passive homing missiles

open access: yesOpen Astronomy, 2022
Proportional navigation guidance law (PNG) is widely used for passive homing missiles. But PNG often suffers from inaccurate tracking of target or even failure when the target is maneuvering quickly or releasing artificial decoys.
Li Jixin   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Comparison of Lower Arm Weight and Passive Elbow Joint Impedance Compensation Strategies in Non-Disabled Participants∗ [PDF]

open access: yes, 2023
People with severe muscle weakness in the upper extremity are in need of an arm support to enhance arm function and improve their quality of life. In addition to weight support, compensation of passive joint impedance (pJimp) seems necessary.
Harlaar, Jaap   +3 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Designing Polymer Nanocomposites for X‐Ray Shielding: Mechanisms, Architectures, and Scalable Processing

open access: yesAdvanced Engineering Materials, EarlyView.
This review highlights advances in lightweight, lead‐free polymer nanocomposites for diagnostic X‐ray shielding. By linking filler chemistry, dispersion, architecture, and photon interaction mechanisms, it establishes structure–performance relationships guiding material design.
Aklilu G. Messele   +2 more
wiley   +1 more source

AMESim Based Simulation Study of Closed Cylinder Lifting System

open access: yesShiyou jixie, 2021
In order to improve the offshore drilling efficiency and ensure the drilling safety, the hydraulic principle of closed hydraulic cylinder lifting system was proposed, and the realization method and control logic of 3 key technologies such as load lifting
Li Huan   +4 more
doaj  

Temperature characterisation of an optically-interrogated Rogowski coil

open access: yes, 2014
An investigation into the performance of an optically-interrogated Rogowski coil over temperatures up to 80 °C is presented. Preliminary thermal tests reveal that the sensor response is temperature-dependent and the measurement errors are increased at ...
Philip Orr   +5 more
core   +1 more source

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