Results 51 to 60 of about 628,667 (249)

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

Attitude of undergraduate medical students towards euthanasia and physician-assisted suicide: a cross-sectional study

Journal of the Pakistan Medical Association
Euthanasia is categorically prohibited in Pakistan by Islamic law, but a clash of opinions among doctors and human rights advocates still prevails. As a result, medical students are becoming concerned about its practice and this problem needs to be ...
Mahnoor, Aiza Noor Shahid, Haleema Shafiq, Noman Aslam, Ayesha Ayub   +4 more
doaj   +1 more source

Mitochondrial Protection and Neural Repair via ROS‐Responsive Biomimetic Nanoparticles in Intracerebral Hemorrhage

Advanced Science, EarlyView.
A ROS‐responsive biomimetic nanoparticle platform co‐delivers DIDS and Mdivi‐1 to protect mitochondria and promote neural repair after intracerebral hemorrhage. By targeting LPAR1/VDAC1‐related mitochondrial dysfunction, the nanotherapy reduces oxidative injury, neuronal apoptosis, and blood‐brain barrier disruption, improving neurological recovery and
Ling Gao, Li Peng, Xiaobin Zheng, Cong Tan, Chuang Wang, Qijiang Xiong, Weiming Chen, Zhao Yang   +7 more
wiley   +1 more source

On the Assumed Moral Superiority of Passive over Active Euthanasia [PDF]

Since the inception of the euthanasia debate, the differentiation be-tween active and passive euthanasia – distinguishing between “let-ting die” and “actively killing” – has emerged as a central point of contention. In this paper, we will contend that: a)
Protopapadakis, Evangelos D., Basilaia, Tatia   +1 more
core   +2 more sources

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

Advanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang, Xinyuan Li, Lixia Huang, Xiangcai Zhang, Wujian Ke   +4 more
wiley   +1 more source

Euthasia in Bulgaria - Religious Aspects

Проблеми на постмодерността, 2017
The primary goal of this article is to initiate a profound discussion in Bulgaria by correctly defining the issues and by presenting the views of the 3 traditional for Bulgaria religions: Christianity, Islam and Judaism.
Tsvetomir Todorov
doaj  

Assisted Dying and Voluntary Euthanasia: Exploring Healthcare Professionals’ Perceptions in a Tertiary Care Setting in South India

Preventive Medicine: Research & Reviews
Background: Globally, with the increased focus on palliative care of adding life to years, the need for the right to refuse and dignified death has also commenced.
Ashutosh Kothari, K. C. Premarajan, Adinarayanan Sethuramachandran, Sadhana Subramanian   +3 more
doaj   +1 more source

Passive Euthanasia [PDF]

, 2017
The controversy of passive euthanasia (e.g. the withholding or withdrawing of life-sustaining treatments in patients that are either disabled or terminally ill) has been long-debated because, it has been argued, passive euthanasia violates the physician ...
Hulett, Jennifer, Peterson, Madeline
core  

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao, Wei Feng, Wei Zong, Yi Li, Xinyue Qin, Xinyue Wang, Yubo Yang, Guanhua Chen, Yiting Hou, Xuan Tan, Lin Chen, Ming Zhang, Feng Wang   +12 more
wiley   +1 more source

WITHDRAWING TREATMENT AND KILLING: THE WAYS TO DISTINGUISH

Вісник Харківського національного університету імені В.Н. Каразіна. Серія Філософія, філософські перипетії, 2020
One of the key problems facing bioethics concerns those cases where, due to the limited human and technical resources of medicine, patients are in fact doomed to die.
Kateryna S. Rassudina
doaj   +1 more source