Results 61 to 70 of about 628,667 (249)

Advancing Biotherapeutic Treatment of Ulcerative Colitis Using Lipid Mesophases: Formulation Design and Preclinical Validation

open access: yesAdvanced Science, EarlyView.
Lipid mesophases provide a versatile platform for colon‐targeted delivery of biotherapeutics, protecting them from degradation while enhancing mucoadhesion and enabling localized, controlled release to the inflamed mucosa after oral or rectal administration. In a DSS‐induced colitis model, this strategy reduced disease activity, inflammatory biomarkers,
Rafaela Gazzi   +13 more
wiley   +1 more source

Analysing restrictive and liberal approaches towards assisted suicide and euthanasia [PDF]

open access: yes, 2010
MPhil (Laws)The ‘end of life’ issue in relation to assisted suicide and euthanasia is one of our prime concerns and a most widely discussed phenomenon not only in academic and official literature, but also in day-to-day life.
Matker, Prema S
core   +2 more sources

Therapeutic Peptide‐Programmed Liquid‐Crystalline Topology Switching for pH‐Gated Postoperative Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A VDAP‐programmed liquid‐crystalline depot enables pH‐responsive postoperative immunotherapy for triple‐negative breast cancer. VDAP stabilizes a leakage‐resistant HII mesophase through peptide–lipid electrostatic assembly, whereas tumor acidosis unlocks the matrix and promotes graded topology remodeling toward a bicontinuous Im3̄m cubic phase for ...
Yan Yan   +12 more
wiley   +1 more source

Reframing End-of-Life Jurisprudence: Legal Contours, Bioethical Tensions, and the Evolving Right to Die with Dignity in India

open access: yesSortuz
This paper reflects on the changing legal, ethical, and cultural dimensions of euthanasia, especially passive euthanasia as envisaged by Article 21 of the Constitution of India. The paper maps out the crucial legal landmarks—from Gian Kaur v.
Amitabh Dwivedi
doaj   +1 more source

Euthanasia and Related Practices Worldwide

open access: yes, 1998
The present paper examines the occurrence of matters relating to the ending of life, including active euthanasia, which is, technically speaking, illegal worldwide.
Kelleher, Michael J.   +4 more
core   +1 more source

Rational Surface Engineering Reduces Advanced Glycation End‐Product Adsorption and Improves Implant Integration

open access: yesAdvanced Science, EarlyView.
Targeted surface chemical modification prevents the accumulation of advanced glycation end products (AGEs) on implant surfaces, attenuates inflammation and fibrosis, effectively restores angiogenic activity, and improves osseointegration under diabetic conditions.
Thien Ngoc Le   +13 more
wiley   +1 more source

Euthanasia and ethical dillemas: Human dignity against sanctity of life [PDF]

open access: yesZbornik Radova: Pravni Fakultet u Novom Sadu, 2017
The paper analyses ethical dilemmas and conflicting issues tied to euthanasia and the institutionalization of the right to a dignified death, viewed through a prism of arguments in favour of and against euthanasia, solutions of comparative law and the ...
Simović Darko Z.   +1 more
doaj  

A self‐retaining mouth prop for intraoral access during periodontal surgery in rat models: A technical note

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A mouth prop designed to mimic the oral cavity of rats was made that provided stable, self‐retaining retraction, thereby facilitating oral surgery on rodents. Compared to conventional methods, it decreased surgical time, operator fatigue, and slippage. Its use led to higher efficiency and fewer complications and it was cost effective to produce.
Saravanan Sampoornam Pape Reddy   +5 more
wiley   +1 more source

Involuntary Passive Euthanasia of Brainstem-Damaged Patients: The Need for Legislation - An Analysis and a Proposal [PDF]

open access: yes, 1977
This Comment will examine present medical and legal standards regarding involuntary passive euthanasia of brain-stem-damaged patients and propose a statute to legalize involuntary passive euthanasia under certain restrictive ...
Mueller, Daniel Mark
core   +1 more source

In Vivo Nb4C3Tx MXene‐Assisted Photothermal Therapy of Melanoma in Mice

open access: yesAdvanced NanoBiomed Research, EarlyView.
Nb4C3Tx MXene converts pulsed 1064 nm irradiation into localized heat, producing concentration‐ and time‐dependent melanoma cell killing in vitro and suppressing tumor growth in mice. Histology reveals extensive tumor damage, macrophage‐associated material clearance, and no detectable persistent deposits in examined visceral organs, supporting Nb4C3Tx ...
Anton Roshchupkin   +22 more
wiley   +1 more source

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