Results 41 to 50 of about 19,571,298 (238)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Passive decay heat removal system for water-cooled nuclear reactors [PDF]
, 1990 This document describes passive decay-heat removal system for a water-cooled nuclear reactor which employs a closed heat transfer loop having heat-exchanging coils inside an open-topped, insulated evaporator located inside the reactor vessel, below its ...
Forseberg, C.W.
core +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
A Numerical Research on the Heat Transfer Process for a General Passive Heat Removal System
, 2017 A code module for simulating a general passive heat removal system composed of an elevated water tank, a heat exchanger and pipes connecting them is developed in this paper. Then, a typical heat transfer process in this heat removal system is calculated.
Guo Qiang, Yuan Yidan, Liu Zhuo, Li Wei
core +1 more source
MANAGING A PROLONGED STATION BLACKOUT CONDITION IN AHWR BY PASSIVE MEANS
Nuclear Engineering and Technology, 2013 Removal of decay heat from an operating reactor during a prolonged station blackout condition is a big concern for reactor designers, especially after the recent Fukushima accident.
MUKESH KUMAR +4 more
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
, 2017 Practice has proved that nuclear power technology development and operation of nuclear power is a clean, safe and large-scale provided stable power. AP1000 uses a large number of passive safety technologies.
Daogang Lu, Haiqi Qin, Shengfei Wang
core +1 more source
CAREM - Like PRHRS (Passive Residual Heat Removal System) Reliability Analysis
, 2007 This document reports the reliability analysis of the CAREM-Like PRHRS (Passive Residual Heat Removal System), performed in the context 01 the IAEA Coordinated Research Project on Natural Circulation Phenomena, Modelling, and Reliability of Passive ...
Burgazzi, L.
core +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source