Results 71 to 80 of about 43,258 (202)

Attacks on sexual, reproductive, maternal and newborn healthcare in armed conflict: Accountability for the gendered reverberating effects

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Attacks on sexual, reproductive, maternal and newborn healthcare are an increasingly prominent feature of contemporary armed conflict, yet their gendered effects remain underexamined. This narrative review synthesizes evidence from global health, humanitarian practice, conflict studies, and international law, drawing on examples from Gaza ...
Sunneva Gilmore, Luke Moffett
wiley   +1 more source

Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV.

PLoS Pathogens, 2020
Human cytomegalovirus (HCMV) causes serious complications to immune compromised hosts. Dendritic cells (iDCgB) expressing granulocyte-macrophage colony-stimulating factor, interferon-alpha and HCMV-gB were developed to promote de novo antiviral adaptive ...
Sebastian J Theobald, Christoph Kreer, Sahamoddin Khailaie, Agnes Bonifacius, Britta Eiz-Vesper, Constanca Figueiredo, Michael Mach, Marija Backovic, Matthias Ballmaier, Johannes Koenig, Henning Olbrich, Andreas Schneider, Valery Volk, Simon Danisch, Lutz Gieselmann, Meryem Seda Ercanoglu, Martin Messerle, Constantin von Kaisenberg, Torsten Witte, Frank Klawonn, Michael Meyer-Hermann, Florian Klein, Renata Stripecke   +22 more
doaj   +1 more source

The Enteric Nervous System: An Integrative Hub From Development to Systemic Physiology

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Unlike a static hardwired circuit, the ENS continuously remodels its transcriptional programs and synaptic connectivity in response to three ecological forces: microbial metabolites, immune cell signals and enteroendocrine cues. ABSTRACT The enteric nervous system (ENS) constitutes the largest and most functionally autonomous subdivision of the ...
Mario Cuchillo‐Hilario, Margarita Díaz‐Martínez, Mario Alberto Viazcan‐Carbajal, Victor David González‐Fernández   +3 more
wiley   +1 more source

Real-world data and clinical management experience in passive immunization for respiratory syncytial virus prevention in children

Vaccine: X
Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections in children under 5 years of age worldwide. Currently, there are no approved curative treatments, and clinical management remains primarily focused on ...
Yongping Xie, Xin Cong, Yan Li, Lisu Huang   +3 more
doaj   +1 more source

Clinical progress note: Rotavirus

Journal of Hospital Medicine, EarlyView.
Abstract Rotavirus is a vaccine‐preventable cause of acute, viral gastroenteritis typically characterized by diarrhea, vomiting, and fever. Prior to rotavirus vaccine introduction, nearly all children worldwide had been infected by 5 years of age. Severe rotavirus gastroenteritis causes dehydration and electrolyte derangements, and infants and young ...
Kelsey Thetford, Meghan Hofto
wiley   +1 more source

A real-world based study for immunogenicity and safety for three immunization schedules of polio vaccine

Scientific Reports
To evaluate the immunogencity and safety for three immunization schedules of inactivated poliovirus vaccine (IPV) and bivalent oral poliovirus vaccine (bOPV) for providing a basis for further optimization of the polio sequential immunization schedule. To
Li Sun, Shi-fan Wang, Yi-qing Zhu, Ya-fei Wang, Jun-mian Zhang, Jing-hui Wang, Yan-li Cong, Jing Li, Xiao-qin Liu, Sha-sha Han, Yu Guo, Qi Li   +11 more
doaj   +1 more source

Evaluation of the marking duration of iophenoxic acid (IPA) derivatives in raccoons (Procyon lotor)

The Journal of Wildlife Management, EarlyView.
We evaluated the marking duration and intensity of iophenoxic acid (IPA) analogues in raccoon (Procyon lotor) serum following consumption of test doses encapsulated in a marshmallow or formulated into an oral rabies vaccine bait matrix. The IPA biomarkers demonstrated utility for evaluation of oral rabies vaccination baiting strategies targeting ...
Shylo R. Johnson, Amy J. Davis, Molly R. Selleck, Alison P. Barbee, Steven F. Volker, Are R. Berentsen, David A. Goldade, Amy T. Gilbert   +7 more
wiley   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

Diagnostic antibodies at an inflection point: From discovery platforms to design‐oriented engineering

VIEW, EarlyView.
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song, Lulai Xu, Weilin Wu, Fei Xie, Yantong Pan, Tiantian Yang, Xiaoxia Xu, Yanyin Lin, Lihua Zhang, Jiahui Zhou, Junyou Zhou, Linping Li, Zhanhui Wang, Weijing Yi, Jing Wang   +14 more
wiley   +1 more source