Results 71 to 80 of about 1,168,111 (299)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Wideband passive source localization

Inverse Problems, 2017
Summary: This paper develops a mathematical method for determining the locations of multiple transmitters from passive measurements of the signals at two or more receivers. The method applies to the case of emitters transmitting either wideband or narrowband signals.
Cheney, Margaret, Given, James A.
openaire   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

A Spaceborne Passive Localization Algorithm Based on MSD-HOUGH for Multiple Signal Sources

Remote Sensing
Recently, the passive synthetic aperture (PSA) technique has been used in passive localization to improve the position accuracy of single source by estimating the Doppler parameter of the received signal.
Liting Zhang, Hao Huan, Tao Ran, Shangyu Zhang, Yushu Zhang, Hao Ding   +5 more
doaj   +1 more source

Bias Compensation for AOA-Geolocation of Known Altitude Target Using Single Satellite

IEEE Access, 2019
To reduce the passive localization bias caused by the nonlinearity between the target position and measurements under high noise level and poor geometry conditions, the bias compensation method for known altitude target geolocation using angles of ...
Chaoxin He, Min Zhang, Fucheng Guo
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Matched Field Processing Based on Least Squares with a Small Aperture Hydrophone Array

Sensors, 2016
The receiver hydrophone array is the signal front-end and plays an important role in matched field processing, which usually covers the whole water column from the sea surface to the bottom. Such a large aperture array is very difficult to realize.
Qi Wang, Yingmin Wang, Guolei Zhu
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Performance Analysis and Dimension-Reduction Taylor Series Algorithms for Locating Multiple Disjoint Sources Based on TDOA Under Synchronization Clock Bias

IEEE Access, 2018
Time difference of arrival (TDOA) localization technology, which does not require the time stamp of the source signals, is playing an increasingly important role in passive localization.
Xin Chen, Ding Wang, Jiexin Yin, Ying Wu
doaj   +1 more source