Solid Dispersion Characteristics of an Oscillatory Microfluidic Mixer: An Experimental and Numerical Investigation. [PDF]
Lu Y, Sun H, Qin Y.
europepmc +1 more source
VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang +7 more
wiley +1 more source
Physiologically-Guided Ultrafiltration: A Proposed Ultrasound Framework for Individualized Volume Removal During Hemodialysis. [PDF]
Patel S, Bootwala A, Green A.
europepmc +1 more source
A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun +12 more
wiley +1 more source
Echocardiographic assessment of left atrial structure and function in severe aortic stenosis with preserved vs. reduced left ventricular ejection fraction. [PDF]
Zhang Y, Mu Y.
europepmc +1 more source
Ti substitution stabilizes Co‐free high‐Ni layered oxides through both structural and electronic effects. TiO6 octahedra act as compensatory structural units that help interrupt cooperative Jahn–Teller distortion and suppress detrimental phase transitions, while the electron‐withdrawing inductive effect of Ti stabilizes the oxygen lattice. As a result,
Bixian Ying +19 more
wiley +1 more source
Spatiotemporal Stability of Persistent Atrial Fibrillation Sources: Stable Source or Disease Progression? [PDF]
Gagyi RB +6 more
europepmc +1 more source
A pneumatic energy‐buffering strategy transforms transient and intermittent footsteps into quasi‐continuous electrical energy for a self‐powered wearable biosensing platform. The footwear‐integrated air‐pumping harvester, combined with the rationally designed power‐management system, powers a wearable ankle PPG device with reduced motion artifacts ...
Ji‐Seok Kim +8 more
wiley +1 more source
Primary pulmonary leiomyosarcoma in a patient with disseminated pulmonary tuberculosis and constrictive pericarditis. [PDF]
Van Der Westhuizen S +5 more
europepmc +1 more source
An innovative hybrid passive cooler integrates a porous radiative coating and an atmospheric moisture‐harvesting hydrogel within a melamine sponge skeleton, synergizing radiative cooling, sensible‐heat absorption, and latent‐heat evaporation. It maintains an average 8.3°C sub‐ambient cooling under sunlight and a maximum ∼42.4°C drop under 2000 W·m−2 ...
Qingyuan Du +6 more
wiley +1 more source

