Results 31 to 40 of about 127,674 (258)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Geopolymer foam as a passive fire protection
MATEC Web of Conferences, 2018 More than 200 firefighters and 40 fire engines were involved in battling the blaze of Grenfell Tower in June 2017. Despite the heroic efforts of fire brigades the more than 80 people died.
Łach Michał +3 more
doaj +1 more source
Вестник СибАДИ, 2017 The article is devoted to the structure and description development of the technical solutions which used in the stand design for studying the dynamics of the transport and technological machines operator vibration protection combined system which used ...
Y. A. Buriyan +3 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Frontiers in ImmunologyBackgroundCoxsackievirus A5 (CV-A5) has re-emerged as an important pathogen associated with hand, foot, and mouth disease (HFMD) in young children. However, the antigenic structure of CV-A5 and the key determinants responsible for neutralizing antibody ...
Chen Wang +12 more
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
地质科技通报Guizhou Province is located in Southwest of China, with many mountains and hills, and is a typical karst topography and geomorphology area with frequent geological disasters such as collapses and landslides.
Yancheng LU +4 more
doaj +1 more source
Protection Schemes in HPON Networks Based on the PWFBA Algorithm
Sensors, 2022 In this paper, possibilities for network traffic protection in future hybrid passive optical networks are presented, and reasons for realizing and utilizing advanced network traffic protection schemes for various network traffic classes in these networks
Rastislav Róka +5 more
doaj +1 more source
Human rotavirus in lambs: infection and passive protection [PDF]
Infection and Immunity, 1977 A human stool filtrate containing rotavirus which was administered orally to gnotobiotic lambs caused diarrhea, virus excretion, development of antibodies to rotavirus, and pathological changes in the villi of the small intestine. Thus, lambs may serve as experimental animals for the study of human rotavirus infections.
D R, Snodgrass +3 more
openaire +2 more sources