Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Modeling of spreading of the melted corium jet inside the pool of emergency heat removal during severe accidents at NPP [PDF]
Important nuclear power safety problem in touch with modeling of melted corium jet spreading inside the coolant pool is considered in the paper. It appears by development of the passive protection systems against se-vere accidents.
I. V. Kazachkov, O. V. Konoval
doaj
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source
Problem of corium melt coolability in passive protection systems against severe accidents in the containment [PDF]
Paper is devoted to the development of the mathematical model and analysis of the problem of corium melt interaction with low-temperature melting blocks in the passive protection systems against severe accidents at the NPP, which is of high importance ...
Ali Kalvand, I. V. Kazachkov
doaj
Determinants of Cancer Early Detection Behaviors:Application of Protection Motivation Theory [PDF]
Background: Cancer is account for 13% of all deaths around the world and is the third cause of mortality in Iran. More than one third of these cases are pre-ventable and about 33% are curable with early detection.
Zohreh Rahaei +3 more
doaj +1 more source
Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai +7 more
wiley +1 more source
Mechanism of protection induced by group A Streptococcus vaccine candidate J8-DT: contribution of B and T-cells towards protection. [PDF]
Vaccination with J8-DT, a leading GAS vaccine candidate, results in protective immunity in mice. Analysis of immunologic correlates of protection indicated a role of J8-specific antibodies that were induced post-immunization.
Manisha Pandey +2 more
doaj +1 more source
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal +2 more
wiley +1 more source
La modélisation au service de la conception des ouvrages de protection : étude du site avalancheux de Taconnaz [PDF]
Optimiser la conception des ouvrages de protection contre les avalanches est une priorité pour la sécurité en montagne. À partir d'une étude réalisée dans le cadre des travaux de renforcement de l'ouvrage paravalanche du glacier de Taconnaz, construit ...
Mohamed Naaim, Thierry Faug, Florence Naaim-Bouvet et Nicolas Eckert
doaj +2 more sources
Optimal passive-damping design using a decentralized velocity-feedback H-Infinity approach [PDF]
In this work, a new strategy to design passive energy dissipation systems for vibration control of large structures is presented. The method is based on the equivalence between passive damping systems and fully decentralized static velocity-feedback ...
F. Palacios-Quiñonero +3 more
doaj +1 more source

