Results 41 to 50 of about 19,633,862 (302)

Virtual Button and Graphical Interface System Safety Evaluation using System Theoretic Process Analysis (STPA) [PDF]

, 2020
System Theoretic Process Analysis (STPA) is an extremely valuable methodology, especially when used early in a system’s concept phase, for effective and efficient development of safety requirements that address potential safety issues associated with ...
Vernacchia, Mark, Johnston, Jesse
core   +1 more source

System Safety In The News [PDF]

, 2021
Document Reveals that 2016 EgyptAir Crash Likely Caused by Oxygen Mask and Cigarette OSHA Asks Amazon to Improve Safety Procedures After Six Employees Die in ...
Muniak, Charles
core   +1 more source

Research and Evaluation for Passive Safety System in Low Pressure Reactor

Science and Technology of Nuclear Installations, 2015
Low pressure reactor is a small size advanced reactor with power of 180 MWt, which is under development at Nuclear Power Institute of China. In order to assess the ability and feasibility of passive safety system, several tests have been implemented on ...
Peng Chuanxin, Zhuo Wenbin, Chen Bingde, Nie Changhua, Huang Yanping   +4 more
doaj   +1 more source

Model-Based Systems Engineering for System Safety: An Introduction [PDF]

, 2019
Model-based systems engineering (MBSE) has gained momentum as the predominant method of analyzing and deriving system requirements, as well as of verifying and validating system performance.
Oliver, Patrick
core   +1 more source

Model Based Functional Safety – How Functional Is It? [PDF]

, 2022
As the engineering world embraces Model Based System Engineering (MBSE), the system safety discipline should also enfold and support MBSE methodology and approaches. The need for Model Based Functional safety, as part of the established system safety and
Hendrix, Barry, Rachele, Brian, Lewis, Thomas, Emery, Melissa   +3 more
core   +1 more source

Risk-informed design optimization method and application in a lead-based research reactor

Nuclear Engineering and Technology, 2023
Risk-informed approach has been widely applied in the safety design, regulation, and operation of nuclear reactors. It has been commonly accepted that risk-informed design optimization should be used in the innovative reactor designs to make nuclear ...
Jiaqun Wang, Qianglong Wang, Jinrong Qiu, Jin Wang, Fang Wang, Yazhou Li   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

'Technical Safety’ or ‘System Safety’? Why Names Matter [PDF]

, 2014
By providing safety and risk management consulting services, we have the opportunity to be regularly involved with clients from a number of different industries.
Oliva, Sergio, Lopez, Ricardo
core  

Potential of heavy goods vehicle countermeasures to reduce the number of fatalities in crashes with vulnerable road users in Sweden

Traffic Safety Research
Heavy Goods Vehicles (HGVs) are involved in a large share of all serious and fatal collisions. Among these, about 30% are collisions involving Vulnerable Road Users (VRUs).
Tania Dukic Willstrand, Kristian Holmquist, Rikard Fredriksson, Matteo Rizzi   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source