Results 61 to 70 of about 30,191 (258)

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

Advanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong, Wenlong Chen, Fanglong Liu, Shengyi Zhou, Bolin Yu, Yuying Wang, Xiqian Zhou, Xuehui Wang, Diya Liu, Zhuoyu Zhang, Xinran Wang, Mounia Lalouly, Yiwen Li, Zhefei Du, Tao Yan, Zhihui Xiao, Zhou Zhou, Huanhuan Zhu, Fengyuan Qian, Bowen Zheng, Lin Fang   +20 more
wiley   +1 more source

Passive Ventilation Systems in Historic Togh

Journal of Architectural and Engineering Research
This study investigates the natural ventilation systems integrated into the historical architectural structures of Togh village in the historical province of Dizak in Artsakh.
Manushak Titanyan, Anna Karamyan, Emma Harutyunyan   +2 more
doaj   +1 more source

Are minimum indoor air quality requirements combined with passive retrofit solutions enough to guarantee thermal comfort in southern Spain High Schools? [PDF]

E3S Web of Conferences
This study addresses the challenging research gap of assessing whether passive energy retrofit solutions are adequate for simultaneously achieving indoor air quality and thermal comfort in educational buildings, given the minimum ventilation rate ...
Calama-González Carmen María, Escandón Rocío, Suárez Rafael   +2 more
doaj   +1 more source

passive ventilation The Effect of an Evaporative Cooler on the Thermal Performance of Passive Ventilation System Coupled with EAHE: An Experimental Investigation

Wasit Journal of Engineering Sciences, 2022
An experimental study of a two-storey structure with a passive ventilation system is conducted in August, with the severe summer environment of Kut, Iraq. The experimental model consists of a solar chimney combined with a hybrid cooling system comprised of an Earth-air heat exchanger and an evaporative cooler.
abbas ali ghafouri, Abbas J. Jubear
openaire   +1 more source

Bioinspired Passive Flow Routing to Mitigate Thrombosis in Prosthetic Heart Valves and Cardiovascular Devices

Advanced Science, EarlyView.
Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin, Mark Epshtein, Yahel Talmon, Tirosh Mekler, Itay Or, Mahli Raad, Gil Bolotin, Josué Sznitman, Netanel Korin   +8 more
wiley   +1 more source

Temperature‐ and Light‐Regulated Liquid Crystal Smart Window for Dynamic Control of Daylight and Solar Heat in All‐Weather Conditions

Angewandte Chemie, EarlyView.
An environmentally adaptive smart window based on the interplay of light‐driven molecular motors and liquid crystal (LC) polymers is developed. The window can dynamically switch among three distinct working states: transparent, reflective, and scattering, depending on ambient temperature and solar light intensity, enabling excellent modulation of ...
Yang Zhang, Ying Wu, Wenxuan Liu, Xin Wang, Dirk J. Broer, Ben L. Feringa, Jiawen Chen   +6 more
wiley   +2 more sources

Evaluation of dehumidification and energy-saving effects for a passive dehumidification system combined with energy recovery ventilation [PDF]

E3S Web of Conferences
Passive dehumidification strategies utilizing renewable energy sources and moisture-buffering materials offer effective solutions for reducing indoor humidity and cooling demands for air-conditioning systems in hot and humid areas. We developed a passive
Chen Yulu, Ozaki Akihito, Lee Haksung, Choi Younhee, Arima Yukuse   +4 more
doaj   +1 more source

Airway pressure morphology and respiratory muscle activity during end-inspiratory occlusions in pressure support ventilation

Critical Care, 2020
Background The driving pressure of the respiratory system is a valuable indicator of global lung stress during passive mechanical ventilation. Monitoring lung stress in assisted ventilation is indispensable, but achieving passive conditions in ...
Stella Soundoulounaki, Evangelia Akoumianaki, Eumorfia Kondili, Emmanouil Pediaditis, Georgios Prinianakis, Katerina Vaporidi, Dimitris Georgopoulos   +6 more
doaj   +1 more source

Adaptive and Highly Efficient Thermoregulation Based on Multi‐Dimensional Janus Film

Advanced Science, EarlyView.
A switchable TiO2/MXene/PDMS Janus membrane enables dual‐mode radiative cooling and solar heating, achieving sub‐ambient cooling of 17.89°C and above‐ambient heating of 13.82°C. Adaptive temperature regulation was demonstrated with a low power integrated autonomous smart curtain system, providing a sustainable and energy‐efficient alternative for ...
Yuqing Shi, Yuting Fu, Xiong Yu, Yuao Guo, Yanjun Liu, Dan Luo, Yuanjing Lin   +6 more
wiley   +1 more source

Passive ventilation systems for the safe use of hydrogen

International Journal of Hydrogen Energy, 1996
These are the findings from a computer model study of hydrogen gas leakage in buildings. The gas cloud shape and size was predicted using FLUENT 3.03. This study investigated the influence of building geometry and passive ventilation on the formation of combustible gas clouds.
M.R. Swain, M.N. Swain
openaire   +1 more source