Results 51 to 60 of about 11,580 (269)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Passivity and leveling Husserl, Heidegger and Hugo Ball [PDF]
Filozofija i Društvo, 2016 The first part of this paper explores the kinship in diagnosis of contemporaneity of Hugo Ball and Martin Heidegger. Both thinkers recognize leveling as an important trait of their age.
Prole Dragan
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Journal of Medical Ethics, 2005 The idea of passive euthanasia has recently been attacked in a particularly clear and explicit way by an “Ethics Task Force” established by the European Association of Palliative Care (EAPC) in February 2001. It claims that the expression “passive euthanasia” is a contradiction in terms and hence that there can be no such thing.
Garrard, E., Wilkinson, Stephen
openaire +3 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
SICE Journal of Control, Measurement, and System Integration, 2018 In this paper, a distributed 3-D pose synchronization law is proposed for a group of networked quadrotors. The quadrotor network consisting of multiple quadrotors with dynamics and interconnection topology between them is first defined, and then, the ...
Tatsuya Ibuki +3 more
doaj +1 more source
Educational passivity – from theory to practice
Edukacyjna Analiza Transakcyjna, 2020 The article offers a review of “Passivity at school” by Pierzchała (2013) in terms of the implications for theory and practice of transactional analysis. The main findings from the research project were summarised and compared to other studies concerning
Piotr Jusik
doaj +1 more source