Results 131 to 140 of about 13,458,883 (414)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Stationarity and Co-Integration in Systems with Three National Real Estate Indices [PDF]
This study examines the stochastic properties of the commercial real estate wealth indices for three countries (the U.S., Canada, and the U.K.) and for several property types (aggregate, office, retail, and industrial).
F.C. Neil Myer +2 more
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The Past and Present State of Astronomy Education in Thailand [PDF]
, 1990 Yupa Vanichai
openalex +1 more source
The Long Cycle of Real Estate [PDF]
The experience of the 1985-93 boom/bust in real estate has left industry players nervous about when it might happen again. This paper examines the possible causes and the periodicity of such major real estate cycles. A search of the literature for return
Ronald W. Kaiser
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Appraisers and the Fair Housing Law: Accessibility Requirements for the Disabled [PDF]
In 1988 the Fair Housing Act of 1968 was amended to include the "handicapped" as being protected from discrimination in multiunit housing. The three general categories of discriminatory acts are refusal to make or allow reasonable physical modifications ...
Richard W. Hoyt, Robert J. Aalberts
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Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Études Britanniques ContemporainesThrough the rewriting of the lives of famous past British writers (or characters), contemporary author Peter Ackroyd’s works explore fictional elements while preserving a high level of referential accuracy.
Lise Lefebvre
doaj +1 more source