Results 51 to 60 of about 27,572 (264)
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Soliman Magnificul – “al doilea Solomon”
TheoRhēma, 2020 This article aims to discover how the imaginary descendants are perpetuated on command by emperors and kings. That is, how Soliman becomes the new Solomon, the new Alexander, the new Caesar in relation to the emulations of his empire when it reached its
Daniel Nițulescu
doaj
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
The Primary Tool for the Church Leader
Kairos (English Ed.), 2010 The place and importance of Scripture as the primary tool to be used by a church leader is often affirmed at the beginning of ministry, but is often marginalized by the pressures of ministerial activities.
Thomas Sibley
doaj
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Economía, Sociedad y Territorio, 2006 De la revisión de las normas constitucionales y legales en los códigos electorales del país se concluye que existen diferentes niveles de restricciones para partidos políticos y para ministros de culto, principalmente por razones históricas.
ALEJANDRO DÍAZ DOMÍNGUEZ
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
#ChurchToo, Kekerasan Seksual di Gereja dan Penguatan Komunitas
Dunamis: Jurnal Teologi dan Pendidikan Kristiani. The hashtag movement like #ChurchToo has become one of the ways for sexual violence survivors to express their experiences of sexual violence they have experienced in the church. #ChurchToo has an influence not only on the survivors' attitudes but also
Ruth Rosani Saiya +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source