Results 61 to 70 of about 27,572 (264)

Pedeapsa cu moartea și problematica iertării păcatului sfidător deliberat

open access: yesTheoRhēma, 2013
The current study tackles two issues. The first one is the issue of the need for understanding the problem of the inexpiable sin and the application of the death penalty within the OT Israel.
Florin Iacob
doaj  

Rev. Dr. Muriel M. Spurgeon Carder (1922–2023): A Canadian Baptist Renaissance Woman

open access: yesReligions
“Renaissance Woman” is a colloquial expression for someone who excels above and beyond normal in a wide variety of tasks, and Rev. Dr. Muriel Spurgeon Carder (1922–2023) deserves that title, for she was an ordained Canadian Baptist missionary who worked ...
Gordon L. Heath
doaj   +1 more source

El cuento de El joven pastor en poder de los asaltantes (ATU 958) a la luz de nuevos testimonios en el norte de África / The Tale of El joven pastor en poder de los asaltantes (ATU 958) in Light of New Testimonies in North Africa

open access: yesBoletín de Literatura Oral, 2018
Resumen. En el presente artículo se publican cuatro versiones bereberes del cuento El joven pastor en poder de los asaltantes que nos obligarán a replantearnos las teorías acerca del origen y de la distribución del relato.
Óscar Abenójar
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Konflikt katolicko-ewangelicki w Osiecznej w latach 1656–1769

open access: yesActa Universitatis Lodziensis: Folia Historica, 2017
Osieczna, niewielkie miasto leżące 10 km od Leszna, w XVII i XVIII w. była areną konfliktu dwóch wyznań chrześcijańskich – katolików i ewangelików. Głównym powodem niepokojów wyznaniowych i w konsekwencji upadku gminy ewangelickiej był potop szwedzki ...
Adrian Gendera
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Development of a Christian Pastoral care and counselling model to support recovery of schizophrenia patients in Maluku

open access: yesHTS Teologiese Studies/Theological Studies
The development of the Christian Pastoral Care and Counselling (CPCC) approach aims to support the recovery process of schizophrenia patients, who have not been appropriately handled by the church.
Monike Hukubun   +2 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

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