Results 61 to 70 of about 113,621 (314)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Spiritual diagnostic criteria in an African setting: The case of baruti in Limpopo province, South Africa

Theologia Viatorum, 2019
In many provinces of South Africa, especially in the indigenous societies, baruti (pastors) are consulted for different purposes, paramount among them being the execution of good health.
Nare J. Masola, Salome T. Sigida, Elizabeth M. Khorommbi   +2 more
doaj   +1 more source

Concerns of Pastoral Ministry With a Biblical Perspective From the Gospel of Mark

, 1982
The area of study for this paper was pastoral ministry. The research focused on three areas of concern: the recruitment of persons for pastoral ministry; the attrition of pastors from the parish ministry: and, the training of ministers
Baker, Merlin C
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Riglyne vir voortgesette teologiese opleiding: Uitdagings vir die AGS-kerk

Verbum et Ecclesia, 2010
Guidelines for continuous theological training: Challenges for the Apostolic Faith Mission church Qualitative research done amongst a section of the broader membership as well as a region of the Apostolic Faith Mission (AFM) church has identified the ...
Andries Putter
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Information Seeking Behavior Of The Clergy

International Journal of Librarianship
This study examines the information-seeking behavior of the clergy using parish pastors in the Redeemed Christian Church of God (RCCG) in Agbarho community in Delta State as a case study. The study seeks to identify the information needs, the sources of
Angela Chiwendu Nweke, Ademola Ferdinand Omosekejimi, Obioma Deborah Okoli   +2 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Et «makedonsk kall»

Scandinavian Journal for Leadership & Theology
A “Macedonian Calling”: Pastors’ perspectives on declining church attendance within the ecclesiological dynamic between folk church and faith community The Sunday worship service, in Lutheran ecclesiology, is the place where the Word is proclaimed, and
Stephen Sirris, Frode Fjeldbraaten
doaj   +1 more source

The pastor as moral guide [PDF]

, 2000
Miles, Rebekah. The pastor as moral guide. Minneapolis: Augsburg Fortress, 1999.
O\u27Connor, Thomas St. James
core   +1 more source