Results 71 to 80 of about 113,621 (314)

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Gedagtes oor die arbeidsregtelike posisie van predikante, pastore en priesters as werknemers van die kerk

open access: yesHTS Teologiese Studies/Theological Studies, 2015
Thoughts on the labor law position of pastors and priests as employees of the church. The issue of labour-law relationships between pastors or priests and their employers (churches) is controversial because they (pastors or priests) are often regarded ...
Fanie van Jaarsveld
doaj   +1 more source

Journal of African Christian Biography: v. 5, no. 2 [PDF]

open access: yes, 2020
A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: Women / Bilingual (French): 1.
Essamuah, Casely   +4 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Media Art in Worship: The Potential for a New Liturgical Art, Its Pastoral and Theological Challenges [PDF]

open access: yes, 2004
(excerpt) I am especially pleased to be among you, because I have had the gift of reflecting on worship in the ELCA in the past, thanks to the late Paul Nelson of blessed memory and Scott Weidler of your Worship Office.
Crowley, Eileen D.
core   +1 more source

Pastoral Leases and Non-Pastoral Land Use [PDF]

open access: yesSSRN Electronic Journal, 2002
The paper reviews pastoral lease arrangements across jurisdictions in Australia and the extent to which these affect the emergence of non- pastoral land uses. Some comparisons are also made with pastoral lease arrangements in New Zealand, which has a history and pattern of pastoral lease administration and land development similar to Australia.
openaire   +2 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

‘BRITANNIA'S PASTORALS.’ [PDF]

open access: yesThe Library, 1918
n ...
openaire   +1 more source

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