Results 91 to 100 of about 740,254 (291)
Effect of Utility Cut Patching on Pavement Deterioration
Journal of King Saud University: Engineering Sciences, 1992 Utility Cut Patching (UCP) is a major cause of pavement deterioration in city streets. The streets of the city of Riyadh are no exception. A study was undertaken to investigate factors related to UCP and possibly contributing to pavement deterioration ...
Abdul-Rahman S. Al-Suhaibani +2 more
doaj +1 more source
The third dimension in landscape metrics analysis applied to Central Alentejo-Portugal [PDF]
, 2010 Landscape metrics have been widely developed over the last two decades, although the question remains: How does landscape metrics relates with ecological processes?
Batista, Teresa +2 more
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Transfinite Patches for Isogeometric Analysis
MathematicsThis paper extends the well-known transfinite interpolation formula, which was developed in late sixties by the applied mathematician William Gordon at the premises of General Motors as an extension of the pre-existed Coons interpolation formula. Here, a conjecture is formulated, which claims that the meaning of the involved blending functions can be ...
openaire +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Understanding the Patch Dynamics of a few Homogenous and Heterogenous Vegetational Patches [PDF]
Nature Environment and Pollution TechnologyVariations in size and shape distinguish vegetation patches across different ecosystems. Nonetheless, recent research highlights notable parallels in the dynamics of these patches and the mechanisms governing their formation and persistence.
Rekha G. Dhammar, Kunal N. Odedra and B. A. Jadeja
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Analysis of Multilayer Patch Antenna [PDF]
International Journal of Scientific Research in Physics and Applied Sciences, 2019 P. Jothilakshmi +2 more
openaire +1 more source