Results 181 to 190 of about 13,945,334 (387)

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

The Patch Test Clinic

, 1978

openalex   +1 more source

Atopy patch tests, together with determination of specific IgE levels, reduce the need for oral food challenges in children with atopic dermatitis [PDF]

, 2001
Charles Christoph Roehr, Susanne Reibel, Mandy Ziegert, Christine Sommerfeld, Ulrich Wahn, B. Niggemann   +5 more
openalex   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Thermography: High sensitivity and specificity diagnosing contact dermatitis in patch testing

Allergology International, 2019
Background: Patch testing of contact allergens to diagnose allergic contact dermatitis (ACD) is a traditional, useful tool. The most important decision is the distinction between allergic and irritant reactions, as this has direct implications on ...
Florian Anzengruber, Fayez Alotaibi, Lilian S. Kaufmann, Adhideb Ghosh, Martin R. Oswald, Julia-Tatjana Maul, Barbara Meier, Lars E. French, Mathias Bonmarin, Alexander A. Navarini   +9 more
doaj  

Positive patch‐test reactions to para‐phenylenediamine, their clinical relevance and the concept of clinical tolerance [PDF]

, 2001
Yuin‐Chew Chan, See‐Ket Ng, Chee‐Leok Goh   +2 more
openalex   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Atopy patch test

Indian Journal of Dermatology, Venereology and Leprology, 2019
Abhishek De, Sandipan Dhar, Varsha Vaidyanathan, Aarti Sarda   +3 more
openaire   +2 more sources

Clinical evaluation of antianginal efficacy of nitroglycerin transdermal patch (NT-1) using multi-step treadmill exercise test. Double-blind comparative test between two doses.

, 1987
KAZUSHIGE KATO
openalex   +2 more sources

Screening for acetaldehyde dehydrogenase 2 genotype in alcohol-induced asthma by using the ethanol patch test [PDF]

, 2001
Hiroto Matsuse, Terufumi Shimoda, Chizu Fukushima, Kazuko Mitsuta, Tetsuya Kawano, Shin-ya Tomari, Sachiko Saeki, Yuki Kondoh, Ikuko Machida, Yasushi Obase, Sadahiro Asai, Shigeru Kohno   +11 more
openalex   +1 more source