Results 41 to 50 of about 199,906 (316)

Astemizole Sensitizes Adrenocortical Carcinoma Cells to Doxorubicin by Inhibiting Patched Drug Efflux Activity

Biomedicines, 2020
Adrenocortical carcinoma (ACC) presents a high risk of relapse and metastases with outcomes not improving despite extensive research and new targeted therapies.
Anida Hasanovic, Méliné Simsir, Frank S. Choveau, Enzo Lalli, Isabelle Mus-Veteau   +4 more
doaj   +1 more source

Identifying Patch Correctness in Test-Based Program Repair

, 2018
Test-based automatic program repair has attracted a lot of attention in recent years. However, the test suites in practice are often too weak to guarantee correctness and existing approaches often generate a large number of incorrect patches. To reduce
Huang, Gang, Liu, Xinyuan, Xiong, Yingfei, Zeng, Muhan, Zhang, Lu   +4 more
core   +1 more source

Inhibiting hedgehog signal by a patched-1 antibody [PDF]

Cell Discovery
Qinli Hu, Xiaofeng Qi, Linda Donnelly, Xiaochun Li   +3 more
doaj   +2 more sources

A Residual N-Terminal Peptide Enhances Signaling of Depalmitoylated Hedgehog to the Patched Receptor

Journal of Developmental Biology
During their biosynthesis, Sonic hedgehog (Shh) morphogens are covalently modified by cholesterol at the C-terminus and palmitate at the N-terminus.
Sophia F. Ehlers, Dominique Manikowski, Georg Steffes, Kristina Ehring, Fabian Gude, Kay Grobe   +5 more
doaj   +1 more source

Fast Shadow Detection from a Single Image Using a Patched Convolutional Neural Network

, 2018
In recent years, various shadow detection methods from a single image have been proposed and used in vision systems; however, most of them are not appropriate for the robotic applications due to the expensive time complexity. This paper introduces a fast
Hosseinzadeh, Sepideh, Shakeri, Moein, Zhang, Hong   +2 more
core   +1 more source

Qualitative picture of a new mechanism for high-Tc superconductors [PDF]

, 2003
Xu et al. observed enhanced Nernst effect and Iguchi et al. observed patched diamagnetism, both well above $T_c$ in underdoped high-$T_c$ superconductors (HTSCs). A new mechanism is proposed here, which seems to naturally explain, at least qualitatively,
Ashcroft N. W., Chia-Ren Hu
core   +1 more source

Evaluation of YLT method to estimate the load carrying capacity of one-way patched reinforced concrete slab under concentrated load

International Journal of Applied Mechanics and Engineering, 2023
An unsaturated polyester resin (UPR) mortar was applied to repair the damage to the tension zone's one-way reinforced concrete (RC) slabs. The load carrying capacity of the patched RC slab is of interest to justify the effectiveness of the repair.
Stefanus Adi Kristiawan, Achmad Basuki, Agus Supriyadi, Bambang Santosa, Sofa Marwoto   +4 more
doaj   +1 more source

Marginal Fermi Liquid with a Two-Dimensional Patched Fermi Surface

, 1999
We consider a model composed of Landau quasiparticle states with patched Fermi surfaces (FS) sandwiched by states with flat FS to simulate the ``cold'' spot regions in cuprates. We calculate the one particle irreducible function and the self-energy up to
A. FERRAZ, T. SAIKAWA, Z. Y. WENG, Zheleznyak A. T.   +3 more
core   +1 more source

Decoding billions of integers per second through vectorization [PDF]

, 2015
In many important applications -- such as search engines and relational database systems -- data is stored in the form of arrays of integers. Encoding and, most importantly, decoding of these arrays consumes considerable CPU time.
Aksyonoff A, Büttcher S, Jones DM, Witten IH   +3 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source