Results 51 to 60 of about 178,768 (314)

InternalBlue - Bluetooth Binary Patching and Experimentation Framework

open access: yes, 2019
Bluetooth is one of the most established technologies for short range digital wireless data transmission. With the advent of wearables and the Internet of Things (IoT), Bluetooth has again gained importance, which makes security research and protocol ...
Bluetooth Core Bluetooth SIG.   +8 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Computer program for interplanetary conic patching [PDF]

open access: yes, 1968
Computer program enables study of one-way transfers, single and double planet flybys, single and double planet stopovers, or mixed flyby and stopover trajectories.
Davis, D. A., Gussow, D. G.
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

A T-lymphoma transmembrane glycoprotein (gp180) is linked to the cytoskeletal protein, fodrin. [PDF]

open access: yes, 1985
A major mouse T-lymphoma surface glycoprotein (gp180) has been identified by labeling cells with 125I and [3H]glucosamine. After ligand-induced receptor patching and/or capping, the amount of gp 180 in the membrane-associated cytoskeleton fraction ...
Bourguignon, LY   +3 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Influence of Patching on the Shear Failure of Reinforced Concrete Beam without Stirrup

open access: yesInfrastructures, 2021
Deteriorated concrete cover, e.g., spalling or delamination, especially when it occurs at the web of a reinforced concrete (RC) beam within the shear span, can reduce the shear capacity of the beam.
Stefanus Adi Kristiawan   +2 more
doaj   +1 more source

Applications of patching to quadratic forms and central simple algebras

open access: yes, 2009
This paper provides applications of patching to quadratic forms and central simple algebras over function fields of curves over henselian valued fields.
A. Borel   +30 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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