Results 131 to 140 of about 1,191 (170)
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A Stereocontrolled Access to (±)‐, (−)‐, and (+)‐Patchouli Alcohol
Helvetica Chimica Acta, 1981AbstractThe racemate and both enantiomers of patchouli alcohol have been synthesized by stereocontrolled routes. The olfactive properties of the patchouli alcohols prepared are reported.
Ferdinand Näf +3 more
openaire +1 more source
Tetrahedron Letters, 1984
Abstract The first total synthesis of (±)-hydroxy patchouli alcohol (3) and the corresponding (±)-carboxylic acid 4, the biooxidation products of patchouli alcohol (2) has been achieved. (±)-Norpatchoulenol (1) has also been synthesized by the biogenetic route via 3 and 4.
Haruki Niwa +3 more
openaire +1 more source
Abstract The first total synthesis of (±)-hydroxy patchouli alcohol (3) and the corresponding (±)-carboxylic acid 4, the biooxidation products of patchouli alcohol (2) has been achieved. (±)-Norpatchoulenol (1) has also been synthesized by the biogenetic route via 3 and 4.
Haruki Niwa +3 more
openaire +1 more source
Preventive Activity of Patchouli Alcohol Against Colorectal Cancer and Diabetes
SSRN Electronic Journal, 2022Patchouli alcohol (PA) is a tricyclic sesquiterpene and the dominant bioactive component in oil extracted from the aerial parts of Pogostemon cablin (patchouli). It has been reported to possess diverse health-beneficial activities, including anti-inflammatory, antiobese, and anticancer ...
Jihye, Lee, Hee-Seop, Lee, Seong-Ho, Lee
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Chemischer Informationsdienst, 1977
AbstractDurch Spaltung von Patchoulialkohol (I) mit Bleitetraacetat/Calciumcarbonat in siedendem Benzol erhält man in 40%iger Aus ‐ beute das Keton (II), das mit Lithiumaluminiumhydrid ein 7:3‐Gemisch der Alkohole (IIIa) und (IIIb) ergibt und an einer hoch aktiven Kieselgelsäule zum Alkohol (IV) cyclisiert wird.
A. F. THOMAS, M. OZAINNE
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AbstractDurch Spaltung von Patchoulialkohol (I) mit Bleitetraacetat/Calciumcarbonat in siedendem Benzol erhält man in 40%iger Aus ‐ beute das Keton (II), das mit Lithiumaluminiumhydrid ein 7:3‐Gemisch der Alkohole (IIIa) und (IIIb) ergibt und an einer hoch aktiven Kieselgelsäule zum Alkohol (IV) cyclisiert wird.
A. F. THOMAS, M. OZAINNE
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An enantiospecific total synthesis of (−)-patchouli alcohol
Tetrahedron: Asymmetry, 2005An enantiospecific total synthesis of patchouli alcohol, starting from the readily available monoterpene (R)-carvone, has been accomplished. A tandem double Michael reaction-alkylation sequence and single electron mediated 6-endo trig cyclisation reaction have been employed as key steps.
Srikrishna, Adusumilli +1 more
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An Efficient Approach to Patchouli Alcohol Analogues
Helvetica Chimica Acta, 1977AbstractA short approach to the tricyclo [5.3.1.03,8] undecane derivatives 1, 10, 11 and 12 and to the tricyclo [4.3.1.03,7] decane derivative 2, starting from industrially available intermediates, is described. Of the compounds 1, 10, 11, and 12, which possess the ring system of patchouli alcohol, 12 also exhibits a woody, patchouli‐like note.
Ferdinand Näf +2 more
openaire +1 more source
Journal of Essential Oil Research, 2011
Abstract A high-performance centrifugal partition chromatography (HPCPC) method was developed for the preparative separation of patchouli alcohol. The separation was performed with a nonaqueous two-phase solvent system consisting of petroleum ether (bp.30–60°C)-acetonitrile (1:1, v/v) in descending separation mode. A total of more than 2 g of patchouli
Zhiqi Yin, Qingwen Zhang, Wen-Cai Ye
exaly +2 more sources
Abstract A high-performance centrifugal partition chromatography (HPCPC) method was developed for the preparative separation of patchouli alcohol. The separation was performed with a nonaqueous two-phase solvent system consisting of petroleum ether (bp.30–60°C)-acetonitrile (1:1, v/v) in descending separation mode. A total of more than 2 g of patchouli
Zhiqi Yin, Qingwen Zhang, Wen-Cai Ye
exaly +2 more sources
Patchouli Alcohol Dampens Lipopolysaccharide Induced Mastitis in Mice
Inflammation, 2014Patchouli alcohol (PA), a tricyclic sesquiterpene isolated from Pogostemonis Herba, has been known to exhibit antioxidant, anti-inflammatory, and other important therapeutic activities. The aim of this study was to investigate the effects of PA on LPS-induced mastitis in vivo and the possible mechanism.
Yong-Ping, Li +7 more
openaire +2 more sources
Tetrahedron, 1987
Abstract The first total synthesis of the two biooxidation products of patchouli alcohol (2), (±)-hydroxy patchouli alcohol (3) and the corresponding (±)-carboxylic acid 4, has been achieved in highly stereoconcrolled manners. Synthesis of (±)-norpatchoulenol (1), the real odoriferous substance of patchouli oil, has been accomplished by the ...
Haruki Niwa +3 more
openaire +1 more source
Abstract The first total synthesis of the two biooxidation products of patchouli alcohol (2), (±)-hydroxy patchouli alcohol (3) and the corresponding (±)-carboxylic acid 4, has been achieved in highly stereoconcrolled manners. Synthesis of (±)-norpatchoulenol (1), the real odoriferous substance of patchouli oil, has been accomplished by the ...
Haruki Niwa +3 more
openaire +1 more source
Patchouli Alcohol, a Compound from Pogostemon cablin , Inhibits Obesity
Journal of Medicinal Food, 2020Obesity predisposes people to a variety of chronic metabolic diseases. Identification of natural factors that prevent the development of obesity is likely to be the most successful means of ameliorating the current obesity epidemic. Patchouli alcohol is a sesquiterpene alcohol found in Pogostemon cablin and possesses health benefit activities.
Jihye, Lee +2 more
openaire +3 more sources