Results 111 to 120 of about 1,745,820 (365)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Standing with a Bundle of Sticks: The All Substantial Rights Doctrine in Action [PDF]

open access: yes, 2018
This Article provides an overview of the Federal Circuit’s all substantial rights doctrine. Surveying decades of case law, this Article seeks to clarify this confusing area of the law and set out the essential rules for those engaged in patent licensing,
Abate, Mark J, Morten, Christopher J
core   +1 more source

On Competition and the Strategic Management of Intellectual Property in Oligopoly [PDF]

open access: yes, 2009
An innovative firm with private information about its indivisible process innovation chooses strategically whether to apply for a patent with probabilistic validity or rely on secrecy.
Jansen, Jos
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Improving the Performance of a Korean Patent Document Search Model using KorPatBERT-based CPC Classification Model

open access: yesJournal of Intellectual Property
The global competition for technological supremacy is intensifying, prompting every country to focus on securing technological advantages through patent acquisition.
Jaeok Min   +4 more
doaj   +1 more source

Phenolic profile and antioxidant potential of selected plants of Pakistan

open access: yesJournal of Applied Botany and Food Quality, 2014
Antioxidants play an important role in inhibiting and scavenging radicals, thus providing protection to humans against infectious and degenerative diseases. Literature shows that the antioxidant activity is high in medicinal plants.
Imram Imram   +4 more
doaj   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Semantic Consistency and Correctness Verification of Digital Traffic Rules

open access: yesEngineering
The consensus of the automotive industry and traffic management authorities is that autonomous vehicles must follow the same traffic laws as human drivers.
Lei Wan   +5 more
doaj   +1 more source

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