Results 161 to 170 of about 1,320,431 (321)

THE PATENT MEDICINE SITUATION

, 1917
John Phillips Street
openalex   +2 more sources

The Roanoke Voyages. 1584-1590. Documents to Illustrate the English Voyages to North America Under the Patent Granted to Walter Raleigh in 1584 [PDF]

, 1956
C. A. Hutchinson
openalex   +1 more source

Patent Portfolio Races in Concentrated Markets for Technology [PDF]

Patent application numbers grow exponentially in many industries, a phenomenon that has been linked to high fragmentation of patent ownership. Contradicting these findings and theoretical arguments, we show that such fragmentation is not a precondition ...
Florian Jell, Joachim Henkel
core  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

PATENT DUCTUS ARTERIOSUS SOME NOTES ON PROGNOSIS AND ON PULMONARY HYPERTENSION [PDF]

, 1955
Mark Campbell
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Counter Patent [PDF]

, 1971
Circuit for measuring wide range of pulse rates by utilizing high capacity ...
Baumer, W. E., Timm, J. D.
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Coarctation of the Aorta Complicated by Patency of the Ductus Arteriosus [PDF]

, 1951
Arnold L. Johnson, Charlotte Ferencz, F. W. Wiglesworth, Donald L. McRae   +3 more
openalex   +1 more source

Telespectrograph Patent [PDF]

, 1969
Telespectrograph for analyzing upper atmosphere by tracking bodies reentering atmosphere at high ...
Ameer, G. A., Walters, R. M.
core   +1 more source