Results 181 to 190 of about 1,320,431 (321)

Marching toward 100% whole genome sequencing

open access: yesFrontiers in Genetics, 2016
Yih-Horng eShiao
doaj   +1 more source

Study on the Voiding Detection System Using Wearable Device [PDF]

open access: yesInternational Neurourology Journal, 2018
Young Seon Hwang
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Competitive disadvantage through non-existing software patents [PDF]

open access: yes
In a model of sequential patent races, it is examined whether or not introducing a patent law in the home country is beneficial to the firms and the society as a whole given the foreign country already offers patent protection.
Pia Weiss
core  

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

PATENT BREADTH AS AN ENTRY DETERRENT: THE CASE OF VERTICALLY DIFFERENTIATED PRODUCT INNOVATIONS [PDF]

open access: yes
Patents provide very important incentives for innovative activity by enabling innovators to appropriate innovation rents through the granting of exclusive rights on their innovations.
Fulton, Murray E., Yiannaka, Amalia
core   +1 more source

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