Results 191 to 200 of about 1,320,431 (321)

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Using the node importance of patent network to evaluate patent relational value. [PDF]

PLoS One
Guo J.
europepmc   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Developing Automatic-Labeled Topic Modeling Based on SAO Structure for Technology Analysis. [PDF]

PLoS One
Park M, Kim S, Yoon B.
europepmc   +1 more source

Discussion on Surgery of the Patent Ductus Arteriosus (Infected and Uninfected)

, 1946
Jacquelyn Hunter
openalex   +1 more source

STUDIES OF CONGENITAL HEART DISEASE. III. VENOUS CATHETERIZATION AS A DIAGNOSTIC AID IN PATENT DUCTUS ARTERIOSUS, TETRALOGY OF FALLOT, VENTRICULAR SEPTAL DEFECT, AND AURICULAR SEPTAL DEFECT 1 [PDF]

, 1947
L Dexter, Florence W. Haynes, C. Sidney Burwell, Eugene C. Eppinger, Merrill C. Sosman, John M. Evans   +5 more
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

A Case Report of Patent Urachus With Perinatal Cardiac Abnormality. [PDF]

Clin Case Rep
Alzahrani HM.
europepmc   +1 more source

PATENT DUCTUS ARTERIOSUS AND ITS SURGICAL TREATMENT [PDF]

, 1945
Annette Gilchrist
openalex   +1 more source

Endogenous R&D and Intellectual Property Laws in Developed and Emerging Economies [PDF]

The incentive of providing protection of intellectual property has been analyzed, both for an emerging economy as well as for a developed economy. The optimal patent length and the optimal patent breadth within a country are found to be positively ...
Bagchi, Aniruddha, Roy, Abhra
core   +1 more source