Results 221 to 230 of about 1,660,326 (362)
Sporting a virtual future: exploring sports and virtual reality patents using deep learning-based analysis. [PDF]
Lee JW, Song S, Yun J, Han DH, Kim Y.
europepmc +1 more source
“Patent Medicines”—the Pharmacist's Duty in Regard to Them**Address delivered at the December meeting of the Chicago Branch, A. Ph. A. [PDF]
BERNARD FANTUS
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TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
STInt: An integrated dataset covering science, technology and industry information in the pharmaceutical field. [PDF]
Xu S, Liu Z, An X.
europepmc +1 more source
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source
New Therapeutic Options for Fusariosis: A Patent Review (2008-2023). [PDF]
Faccin ID+8 more
europepmc +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
Research on Chinese patent classification based on structured features. [PDF]
Li R, Yu W, Wang S.
europepmc +1 more source
Patents Hinder Collusion [PDF]
We argue that a patent system makes collusion among innovators more difficult. Our simple argument is based on two properties of the patent system. First, a patent not only protects against infringement but also against retaliation by former collusion ...
Juuso Toikka+2 more
core
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source