Results 41 to 50 of about 1,441,892 (337)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Affect of Features of a Microorganism Strain on a Scope of Exclusive Rights

Разработка и регистрация лекарственных средств
Introduction. A launch of larger number of pharmaceutical preparations based on recombinant products and biotechnologies leads to determine a strategy for protection of exclusive rights for subjects implemented into manufacturing process, including ...
F. S. Ivanov, K. V. Nasonova
doaj   +1 more source

Patentability of Biological Material(s) - Essentially, Therapeutic Antibodies - in India

SCRIPTed: A Journal of Law, Technology & Society, 2008
Indian patent practice and jurisprudence with respect to biological materials (including antibodies) is relatively new and thus not well-settled and/or uniform, unlike in the USA or Europe.
Swarup Kumar
doaj   +1 more source

Novel Recurrence Relations for Volumes and Surfaces of n-Balls, Regular n-Simplices, and n-Orthoplices in Real Dimensions

Mathematics, 2022
This study examines n-balls, n-simplices, and n-orthoplices in real dimensions using novel recurrence relations that remove the indefiniteness present in known formulas.
Szymon Łukaszyk
doaj   +1 more source

The Design of Post-Grant Patent Challenges [PDF]

, 2009
This paper proposes a patent challenge mechanism with partial patent rights previously granted to the patent-holder as the challenge reward. Transferring patent rights to a successful challenger raises the incentive to search for patent-defeating ...
Chiou, Jing-Yuan
core  

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

A Deep Learning Model for Automatic Citation Document Recommendation in Non-Obviousness Judgment: Using BERT-for-patents and Contrastive Learning

Journal of Intellectual Property
Patent laws in various countries stipulate that inventions identical to or easily derivable from prior art lack novelty and non-obviousness, rendering them ineligible for registration. To assess these criteria, prior art searches are conducted.
Dongkun Yoo, Jiheon Han
doaj   +1 more source

Does the political will exist to bring quality-assured and affordable drugs to low- and middle-income countries?

Global Health Action, 2019
Background: Increased coverage with antiretroviral therapy for people living with HIV in low- and middle-income countries has increased their life expectancy associated with non-HIV comorbidities and the need for quality-assured and affordable non ...
Eduard J. Beck, Sundhiya Mandalia, Boniface DongmoNguimfack, Eloan Pinheiro, Ellen ‘t Hoen, Pascale Boulet, John Stover, Aashta Gupta, Sandeep Juneja, Vincent Habiyambere, Peter Ghys, Cesar Nunez   +11 more
doaj   +1 more source

Exploring Family Relations between International Patent Applications

Biomath, 2012
In the international system for granting patents for inventions, first patent filings can be followed by subsequent filings at other patent offices within one year. Each such group of related filings constitutes a patent family. Tests are developed as to
Peter Hingley
doaj   +1 more source

Patent Reform and Best Mode: A Signal to the Patent Office or a Step Toward Elimination? [PDF]

, 2012
On September 16, 2011, President Obama signed the America Invents Act (AIA), the first major overhaul of the patent system in nearly sixty years. This article analyzes the recent change to patent law\u27s best mode requirement under the AIA.
Vacca, Ryan G.
core   +2 more sources