Results 31 to 40 of about 325,976 (247)

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

The kinetic relativity theory – hiding in plain sight

Open Physics
A question in physics is whether Special Relativity (SR) is the only theory that explains relativistic behavior. SR measures time dilation by a relative velocity between two frames.
Loen Mark V.
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

mRNA vaccines and therapeutics beyond COVID-19: A review of the global clinical development landscape, low- and middle-income countries involvement and relevance to their contexts

Human Vaccines & Immunotherapeutics
mRNA vaccines demonstrated transformative potential during the COVID-19 pandemic, yet global access to mRNA research, development, and manufacturing capacity remains unequal.
Monica Moschioni, Rafay Anwer Siraji, Romain Dissard, Giulia Segafredo, Hillary Mutungi, Aashima Jain, Rosy Thakur, Neeraj Maurya, Ike James   +8 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

TERM EXTENSION OF DRUG PATENTS IN RUSSIA (REVIEW OF LEGISLATION AMENDMENTS)

Разработка и регистрация лекарственных средств, 2019
The article describes the procedure of patent term extension to be granted on inventions relating to drugs and of granting a supplementary patent in view of recent amendments introduced in the Civil Code of the Russian Federation.
K. V. Osipov
doaj  

Effects of a Multicomponent Mycotoxin Detoxifying Agent on Health and Performance of Weaned Pigs Under Combined Dietary Exposure to Deoxynivalenol (DON) and Zearalenone (ZEN)

Toxins
The aim of the present study was to evaluate the efficacy of a multicomponent mycotoxin detoxifying agent (MMDA, MYCORAID, Patent Co, Mišićevo, Serbia) in weaned pigs receiving contaminated feed with deoxynivalenol (DON) and zearalenone (ZEN).
Jog Raj, Panagiotis Tassis, Klaus Männer, Hunor Farkaš, Zdenka Jakovčević, Marko Vasiljević   +5 more
doaj   +1 more source

Travel Choice Behavior Model Based on Mental Accounting of Travel Time and Cost

Journal of Advanced Transportation, 2021
This paper analyzes the utility calculation principle of travelers from the perspective of mental accounting and proposes a travel choice behavior model that considers travel time and cost (MA-TC model).
Shixu Liu, Jianchao Zhu, Said M. Easa, Lidan Guo, Shuyu Wang, Haoyu Wang, Yijian Xu   +6 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Multi-Mycotoxin Contamination in Serbian Maize During 2021–2023: Climatic Influences and Implications for Food and Feed Safety

Toxins
Mycotoxin contamination in maize poses significant food and feed safety risks, particularly in regions with variable climatic conditions like Serbia. This study investigated the occurrence of regulated mycotoxins in maize harvested across the Republic of
Felipe Penagos-Tabares, Anastasija Todorov, Jog Raj, Hunor Farkaš, Goran Grubješić, Zdenka Jakovčević, Svetlana Ćujić, Jelena Nedeljković-Trailović, Marko Vasiljević   +8 more
doaj   +1 more source