Results 61 to 70 of about 1,745,820 (365)
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
TERM EXTENSION OF DRUG PATENTS IN RUSSIA (REVIEW OF LEGISLATION AMENDMENTS)
Разработка и регистрация лекарственных средств, 2019 The article describes the procedure of patent term extension to be granted on inventions relating to drugs and of granting a supplementary patent in view of recent amendments introduced in the Civil Code of the Russian Federation.
K. V. Osipov
doaj
Life, 2022 The heterogeneity of ribosomes, characterized by structural variations, arises from differences in types, numbers, and/or post-translational modifications of participating ribosomal proteins (RPs), ribosomal RNAs (rRNAs) sequence variants plus post ...
Yih-Horng Shiao
doaj +1 more source
Geocoding of worldwide patent data
Scientific Data, 2019 The dataset provides geographic coordinates for inventor and applicant locations in 18.8 million patent documents spanning over more than 30 years. The geocoded data are further allocated to the corresponding countries, regions and cities.
Gaétan de Rassenfosse +2 more
semanticscholar +1 more source
A Simple Theory of Defensive Patenting [PDF]
, 2006 This paper examines innovating firms’ incentives to engage in defensive patenting. It first establishes a “truce equilibrium” in patent enforcement: when litigation is costly, the equal strength of two symmetric parties’ patent portfolios deters any ...
Chiou, Jing-Yuan
core
The Political Economy of the Research Exemption in American Patent Law [PDF]
, 2016 This Article approaches the research exemption, and related legal developments, as a case study in the political economy of patent law. Part I recounts the history of the research exemption, touching briefly on historical origins but emphasizing ...
Short, Nicholas
core +2 more sources
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
SCRIPTed: A Journal of Law, Technology & Society, 2010 In keeping with the relatively new waiver of the requirement of domestic production under Article 31(f) of TRIPS, the Indian Patents Act 1970 was amended allowing for compulsory license in certain exceptional circumstances.
Swarup Kumar
doaj +1 more source
International patent protection: Time for a fully EU functioning supra-national patent mechanism [PDF]
, 2011 Larger industrial companies have become increasingly global in their functions and aspirations. With regard to patents, it is increasingly common for a multinational company to face alleged infringing acts committed by the same competitor in several ...
Loftus, D
core +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source