Results 71 to 80 of about 1,320,431 (321)
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Experiments on domain adaptation for patent machine translation in the PLuTO project [PDF]
, 2011 The PLUTO1 project (Patent Language Translations Online) aims to provide a rapid solution for the online retrieval and translation of patent documents through the integration of a number of existing state-of-the-art components provided by the project ...
Ceausu, Alexandru +3 more
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Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Journal of Intellectual PropertyTrademarks are marks (symbols, letters, figures, sounds, etc.) used to distinguish one’s goods from those of others. Trademark rights are a type of intellectual property, that protect trademarks and maintain reliability, thereby safeguarding consumers ...
Sol-Bin Hwang +3 more
doaj +1 more source
The Shapley Values on Fuzzy Coalition Games with Concave Integral Form
Journal of Applied Mathematics, 2014 A generalized form of a cooperative game with fuzzy coalition variables is proposed. The character function of the new game is described by the Concave integral, which allows players to assign their preferred expected values only to some coalitions.
Jinhui Pang, Xiang Chen, Shujin Li
doaj +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
Checking the Staats: How Long Is Too Long to Give Adequate Public Notice in Broadening Reissue Patent Applications? [PDF]
, 2011 A classic property rights question looms large in the field of patent law: where do the rights of inventors end and the rights of the public begin? The right of inventors to modify the scope of their claimed inventions, even after the patent issues, is ...
Longo, David M., Ph.D. +1 more
core +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
MODEM CONCEPTIONS ON CONFORMITIES OF THE FOUNDRY TECHNOLOGY DEVELOPMENT
Литьë и металлургия, 2006 The modem conceptions of the foundry technologies development are considered.
A. A. Minaev
doaj