Results 191 to 200 of about 26,374,183 (352)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Patent Analysis of Dental CBCT Machines. [PDF]

Int Dent J
Yeung AWK, Nalley A, Hung KF, Oenning AC, Tanaka R.   +4 more
europepmc   +1 more source

Traces of prior art. An analysis of non-patent references found in patent documents. [PDF]

Research in the area of innovation has pointed out the relevance of conceiving innovation as processes in which a multitude of actors and a variety of interactions play a role.
Callaert, J, Debackere, Koenraad, Thijs, Bart, Van Looy, Bart, Verbeek, Arnold   +4 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Polysaccharide-Based Drug Carriers-A Patent Analysis. [PDF]

Gels
Ilić-Stojanović S, Damiri F, Musuc AM, Berrada M.   +3 more
europepmc   +1 more source

Reaping What You Sow: An Empirical Analysis of International Patent Harmonization. [PDF]

This paper extends analysis of the GATT Uruguay Round qualifiying the impact of international patent harmonization as implied by the TRIPs agreement.PROPERTY RIGHTS ; INTERNATIONAL ...
McCalman, P.
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The History and Prediction of Prebiotics and Postbiotics: A Patent Analysis. [PDF]

Nutrients
Zang T, Han L, Lu Z, Tan L, Liang D, Shen X, Liao X, Liu Y, Ren H, Sun J.   +9 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Revealing Chemical Trends: Insights from Data-Driven Visualization and Patent Analysis in Exposomics Research. [PDF]

Environ Sci Technol Lett
Aurich D, Schymanski EL, de Jesus Matias F, Thiessen PA, Pang J.   +4 more
europepmc   +1 more source