Results 171 to 180 of about 26,374,183 (352)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Research on technology prospect risk of high-tech projects based on patent analysis. [PDF]
PLoS One, 2020 Zhang L, Liu Z.
europepmc +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Analytical techniques and instrumentation: A compilation [PDF]
Technical information on developments in instrumentation is arranged into four sections: (1) instrumentation for analysis; (2) analysis of matter; (3) analysis of electrical and mechanical phenomena; and (4) structural analysis.
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Ekonomika Nauki, 2015 The article presents a scientometrical and patent analysis of a new perspective scientific area called «optogenetics» with the usage of bibliometric data bases Web of Science and Scopus, as well as other analytical tools such as Essential Science ...
A. V. Komarova +2 more
doaj
Sleeping patents: any reason to wake up? [PDF]
Patents are typically characterized as very valuable assets for firms. Nevertheless, there are many patents in a firm's portfolio that are actually never used.
Palomeras, Neus
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
NATIONAL TECHNOLOGICAL INITIATIVE: EVALUATION OF PERSPECTIVES OF RUSSIA'S TECHNOLOGICAL LEADERSHIP
Ekonomika Nauki, 2015 There were analysed scientific-technological solutions which are suggested to be included in the National Technological Initiative «New Production technologies» (NSI-NPT).
N. G. Kurakova, A. N. Petrov
doaj
Idea Generation and New Direction for Exploitation Technologies of Coal-Seam Gas through Recombinative Innovation and Patent Analysis. [PDF]
Int J Environ Res Public Health, 2020 Feng L, Li Y, Liu Z, Wang J.
europepmc +1 more source